Are dose calculations during dose optimization in brachytherapy necessary?

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dc.contributor.author Lahanas, M en
dc.contributor.author Baltas, D en
dc.date.accessioned 2014-03-01T01:18:41Z
dc.date.available 2014-03-01T01:18:41Z
dc.date.issued 2003 en
dc.identifier.issn 0094-2405 en
dc.identifier.uri http://hdl.handle.net/123456789/15154
dc.subject Brachytherapy en
dc.subject Optimization algorithms en
dc.subject.classification Radiology, Nuclear Medicine & Medical Imaging en
dc.subject.other article en
dc.subject.other brachytherapy en
dc.subject.other calculation en
dc.subject.other dosimetry en
dc.subject.other mathematical computing en
dc.subject.other mathematical model en
dc.subject.other priority journal en
dc.subject.other technique en
dc.subject.other Algorithms en
dc.subject.other Brachytherapy en
dc.subject.other Computer Simulation en
dc.subject.other Dose Fractionation en
dc.subject.other Humans en
dc.subject.other Male en
dc.subject.other Models, Biological en
dc.subject.other Models, Statistical en
dc.subject.other Organ Specificity en
dc.subject.other Prostatic Neoplasms en
dc.subject.other Radiation Protection en
dc.subject.other Radiometry en
dc.subject.other Radiotherapy Dosage en
dc.subject.other Radiotherapy Planning, Computer-Assisted en
dc.subject.other Reproducibility of Results en
dc.subject.other Risk Assessment en
dc.subject.other Sample Size en
dc.subject.other Sensitivity and Specificity en
dc.title Are dose calculations during dose optimization in brachytherapy necessary? en
heal.type journalArticle en
heal.identifier.primary 10.1118/1.1580483 en
heal.identifier.secondary http://dx.doi.org/10.1118/1.1580483 en
heal.language English en
heal.publicationDate 2003 en
heal.abstract We consider the problem of anatomy based dose optimization in brachytherapy. A calculation method for some objective functions and their derivatives is proposed which significantly reduces the number of required operations. The optimization in some cases, ignoring a preprocessing step, is independent of the number of sampling points. The idea is that some of the objectives and their derivatives used for dose optimization do not require the explicit calculation of dose values. Dose optimization with the new modified computation method for the objectives and derivatives is, depending on the number of sampling points, up to 100 times faster than the conventional method with dose calculation. (C) 2003 American Association of Physicists in Medicine. en
heal.journalName Medical Physics en
dc.identifier.doi 10.1118/1.1580483 en
dc.identifier.isi ISI:000185379100014 en
dc.identifier.volume 30 en
dc.identifier.issue 9 en
dc.identifier.spage 2368 en
dc.identifier.epage 2375 en

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