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In vivo thermoluminescence dosimetry dose verification of transperineal 192Ir high-dose-rate brachytherapy using CT-based planning for the treatment of prostate cancer

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dc.contributor.author Anagnostopoulos, G en
dc.contributor.author Baltas, D en
dc.contributor.author Geretschlaeger, A en
dc.contributor.author Martin, T en
dc.contributor.author Papagiannis, P en
dc.contributor.author Tselis, N en
dc.contributor.author Zamboglou, N en
dc.date.accessioned 2014-03-01T01:19:02Z
dc.date.available 2014-03-01T01:19:02Z
dc.date.issued 2003 en
dc.identifier.issn 0360-3016 en
dc.identifier.uri http://hdl.handle.net/123456789/15339
dc.subject Brachytherapy en
dc.subject In vivo en
dc.subject Prostate en
dc.subject TLD en
dc.subject.classification Oncology en
dc.subject.classification Radiology, Nuclear Medicine & Medical Imaging en
dc.subject.other Catheters en
dc.subject.other Dosimetry en
dc.subject.other Oncology en
dc.subject.other Thermoluminescence en
dc.subject.other Tumors en
dc.subject.other Treatment planning systems en
dc.subject.other Radiotherapy en
dc.subject.other iridium 192 en
dc.subject.other accuracy en
dc.subject.other analytical error en
dc.subject.other article en
dc.subject.other brachytherapy en
dc.subject.other catheter en
dc.subject.other clinical article en
dc.subject.other computer assisted tomography en
dc.subject.other human en
dc.subject.other male en
dc.subject.other priority journal en
dc.subject.other prostate cancer en
dc.subject.other radiation dose en
dc.subject.other thermoluminescence dosimetry en
dc.subject.other Brachytherapy en
dc.subject.other Calibration en
dc.subject.other Humans en
dc.subject.other Iridium Radioisotopes en
dc.subject.other Male en
dc.subject.other Prostatic Neoplasms en
dc.subject.other Radiotherapy Dosage en
dc.subject.other Radiotherapy Planning, Computer-Assisted en
dc.subject.other Thermoluminescent Dosimetry en
dc.subject.other Tomography, X-Ray Computed en
dc.title In vivo thermoluminescence dosimetry dose verification of transperineal 192Ir high-dose-rate brachytherapy using CT-based planning for the treatment of prostate cancer en
heal.type journalArticle en
heal.identifier.primary 10.1016/S0360-3016(03)00762-4 en
heal.identifier.secondary http://dx.doi.org/10.1016/S0360-3016(03)00762-4 en
heal.language English en
heal.publicationDate 2003 en
heal.abstract Purpose: To evaluate the potential of in vivo thermoluminescence dosimetry to estimate the accuracy of dose delivery in conformal high-dose-rate brachytherapy of prostate cancer. Methods and Materials: A total of 50 LiF, TLD-100 cylindrical rods were calibrated in the dose range of interest and used as a batch for all fractions. Fourteen dosimeters for every treatment fraction were loaded in a plastic 4F catheter that was fixed in either one of the 6F needles implanted for treatment purposes or in an extra needle implanted after consulting with the patient. The 6F needles were placed either close to the urethra or in the vicinity of the median posterior wall of the prostate. Initial results are presented for 18 treatment fractions in 5 patients and compared to corresponding data calculated using the commercial treatment planning system used for the planning of the treatments based on CT images acquired postimplantation. Results: The maximum observed mean difference between planned and delivered dose within a single treatment fraction was 8.57% +/- 2.61% (root mean square [RMS] errors from 4.03% to 9.73%). Corresponding values obtained after averaging results over all fractions of a patient were 6.88% +/- 4.93% (RMS errors from 4.82% to 7.32%). Experimental results of each fraction corresponding to the same patient point were found to agree within experimental uncertainties. Conclusions: Experimental results indicate that the proposed method is feasible for dose verification purposes and suggest that dose delivery in transperineal high-dose-rate brachytherapy after CT-based planning can be of acceptable accuracy. (C) 2003 Elsevier Inc. en
heal.publisher ELSEVIER SCIENCE INC en
heal.journalName International Journal of Radiation Oncology Biology Physics en
dc.identifier.doi 10.1016/S0360-3016(03)00762-4 en
dc.identifier.isi ISI:000186293800033 en
dc.identifier.volume 57 en
dc.identifier.issue 4 en
dc.identifier.spage 1183 en
dc.identifier.epage 1191 en


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