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Stability of DL-poly(lactic acid) in aqueous solutions

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dc.contributor.author Proikakis, CS en
dc.contributor.author Mamouzelos, NJ en
dc.contributor.author Tarantili, PA en
dc.contributor.author Andreopoulos, AG en
dc.date.accessioned 2014-03-01T01:19:33Z
dc.date.available 2014-03-01T01:19:33Z
dc.date.issued 2003 en
dc.identifier.issn 0021-8995 en
dc.identifier.uri http://hdl.handle.net/123456789/15572
dc.subject Biodegradable en
dc.subject Drug delivery systems en
dc.subject Polyesters en
dc.subject Swelling en
dc.subject.classification Polymer Science en
dc.subject.other Bacteria en
dc.subject.other Biodegradation en
dc.subject.other Drug products en
dc.subject.other Formaldehyde en
dc.subject.other Functions en
dc.subject.other Hydrolysis en
dc.subject.other Infrared spectroscopy en
dc.subject.other Light scattering en
dc.subject.other Molecular weight en
dc.subject.other Nuclear magnetic resonance en
dc.subject.other Polycondensation en
dc.subject.other Polyesters en
dc.subject.other Solutions en
dc.subject.other Swelling en
dc.subject.other Viscosity measurement en
dc.subject.other Buffer solutions en
dc.subject.other Organic acids en
dc.subject.other medical application en
dc.subject.other swelling en
dc.title Stability of DL-poly(lactic acid) in aqueous solutions en
heal.type journalArticle en
heal.identifier.primary 10.1002/app.11449 en
heal.identifier.secondary http://dx.doi.org/10.1002/app.11449 en
heal.language English en
heal.publicationDate 2003 en
heal.abstract DL-poly(lactic acid) of molecular weight about 2500 was prepared by polycondensation of lactic acid and characterized by viscosimetry, infrared spectroscopy, light scattering, GPC, and NMR. Tablets made of the above polymer were immersed in buffer solutions at 37°C, and their swelling behavior was recorded as a function of time, in terms of weight gain. In the same experiments, the hydrolytic stability of PLA was assessed by measuring the weight loss after drying the tablets. To inhibit any degradation due to bacteria, formaldehyde was added to the solution as a biostatic factor. © 2002 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 87. en
heal.publisher JOHN WILEY & SONS INC en
heal.journalName Journal of Applied Polymer Science en
dc.identifier.doi 10.1002/app.11449 en
dc.identifier.isi ISI:000179735700010 en
dc.identifier.volume 87 en
dc.identifier.issue 5 en
dc.identifier.spage 795 en
dc.identifier.epage 804 en


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