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Proton beam profiling in soft biological matter by detailed Monte Carlo simulation

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dc.contributor.author Emfietzoglou, D en
dc.contributor.author Nikjoo, H en
dc.contributor.author Papamichael, G en
dc.contributor.author Pathak, A en
dc.date.accessioned 2014-03-01T01:24:54Z
dc.date.available 2014-03-01T01:24:54Z
dc.date.issued 2006 en
dc.identifier.issn 0168-583X en
dc.identifier.uri http://hdl.handle.net/123456789/17501
dc.subject Microdosimetry en
dc.subject Monte Carlo en
dc.subject Protons en
dc.subject Water en
dc.subject.classification Instruments & Instrumentation en
dc.subject.classification Nuclear Science & Technology en
dc.subject.classification Physics, Atomic, Molecular & Chemical en
dc.subject.classification Physics, Nuclear en
dc.subject.other Carrier concentration en
dc.subject.other Computer simulation en
dc.subject.other Ions en
dc.subject.other Monte Carlo methods en
dc.subject.other Protons en
dc.subject.other Biological tissue en
dc.subject.other Dielectric response en
dc.subject.other Electronic energy density en
dc.subject.other Microdosimetry en
dc.subject.other Proton beams en
dc.title Proton beam profiling in soft biological matter by detailed Monte Carlo simulation en
heal.type journalArticle en
heal.identifier.primary 10.1016/j.nimb.2006.03.055 en
heal.identifier.secondary http://dx.doi.org/10.1016/j.nimb.2006.03.055 en
heal.language English en
heal.publicationDate 2006 en
heal.abstract Distributions of relevance to proton beam profiling in soft biological matter are obtained by our Monte Carlo track structure code (MC4), which simulates in an event-by-event mode the electronic losses of light ions and all their secondary electrons in water. We present results on electronic energy density and clustering of interaction events around MeV proton tracks which are associated with important ""local track"" parameters. The detailed character of the simulation based on single-collision cross sections for all the elementary interaction processes allows a probing resolution of the order of nanometers. Since soft biological tissue exists in a liquid/solid like state we compare results obtained by both the oscillator strength properties of the water molecule and the dielectric response of liquid water. Their differences in terms of the nanometric pattern of proton tracks is examined. © 2006 Elsevier B.V. All rights reserved. en
heal.publisher ELSEVIER SCIENCE BV en
heal.journalName Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms en
dc.identifier.doi 10.1016/j.nimb.2006.03.055 en
dc.identifier.isi ISI:000239545000162 en
dc.identifier.volume 249 en
dc.identifier.issue 1-2 SPEC. ISS. en
dc.identifier.spage 670 en
dc.identifier.epage 672 en


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