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Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: The Greek experience

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dc.contributor.author Kalogeridi, MA en
dc.contributor.author Georgolopoulou, P en
dc.contributor.author Kouloulias, V en
dc.contributor.author Kouvaris, J en
dc.contributor.author Pissakas, G en
dc.date.accessioned 2014-03-01T01:58:54Z
dc.date.available 2014-03-01T01:58:54Z
dc.date.issued 2009 en
dc.identifier.issn 0973-1482 en
dc.identifier.uri http://hdl.handle.net/123456789/28780
dc.subject Acoustic neuroma en
dc.subject linear accelerator en
dc.subject local control en
dc.subject stereotactic radiosurgery en
dc.subject.other LINEAR-ACCELERATOR RADIOSURGERY en
dc.subject.other QUALITY-OF-LIFE en
dc.subject.other VESTIBULAR SCHWANNOMA en
dc.subject.other HEARING PRESERVATION en
dc.subject.other SURGICAL-MANAGEMENT en
dc.subject.other SINGLE-INSTITUTION en
dc.subject.other RADIOTHERAPY FSRT en
dc.subject.other NATURAL-HISTORY en
dc.subject.other 13 GY en
dc.subject.other TUMOR en
dc.title Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: The Greek experience en
heal.type journalArticle en
heal.language English en
heal.publicationDate 2009 en
heal.abstract Purpose: To estimate the value of LINAC-based stereotactic radiosurgery (SRS) for the long-term local control of unilateral acoustic neuromas. Materials and Methods: Twenty patients (median age 66; range 57-80 years) with unilateral acoustic neuroma underwent LINAC-based SRS from May 2000 through June 2004 with a dose of 11-12 Gy. The follow-up period ranged from 36 to 84 months (median follow-up period: 55 months). Before SRS none of the patients had useful hearing. The follow-up consisted of repeat imaging studies and clinical examination for assessment of facial and trigeminal nerve function at 6-month intervals for the first year and yearly thereafter. Results: Eleven tumors (58) decreased in size and eight (42) remained stable. One tumor showed a minor increase in size on the MRI done 6 months after SRS in comparison with the pretreatment MRI; however, a subsequent decrease was noticed on the next radiographic assessment and the tumor remained stable from then on. None of the tumors increased in size in the long-term follow-up, thus giving an overall growth control of 100 for the patients in this study. None of the patients had useful hearing before SRS, so hearing level was not assessed during follow-up. No patient developed new, permanent facial or trigeminal neuropathy. Conclusion: LINAC-based SRS with 11-12 Gy provides excellent tumor control in acoustic neuroma and has low toxicity even after long-term follow-up. en
heal.publisher MEDKNOW PUBLICATIONS en
heal.journalName JOURNAL OF CANCER RESEARCH AND THERAPEUTICS en
dc.identifier.isi ISI:000264353700003 en
dc.identifier.volume 5 en
dc.identifier.issue 1 en
dc.identifier.spage 8 en
dc.identifier.epage 13 en


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