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Sonographic findings in severe fetomaternal transfusion

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dc.contributor.author Sifakis, S en
dc.contributor.author Koukoura, O en
dc.contributor.author Konstantinidou, AE en
dc.contributor.author Kikidi, K en
dc.contributor.author Prezerakou, M en
dc.contributor.author Kaminopetros, P en
dc.date.accessioned 2014-03-01T02:00:39Z
dc.date.available 2014-03-01T02:00:39Z
dc.date.issued 2010 en
dc.identifier.issn 0932-0067 en
dc.identifier.uri http://hdl.handle.net/123456789/29123
dc.subject Fetal anemia en
dc.subject Fetomaternal hemorrhage en
dc.subject Fetomaternal transfusion en
dc.subject Middle cerebral artery en
dc.subject Intrauterine intravascular transfusion en
dc.subject Periventricular echogenicity en
dc.subject.classification Obstetrics & Gynecology en
dc.subject.other CRANIAL ULTRASONOGRAPHIC FINDINGS en
dc.subject.other BLOOD-CELL ALLOIMMUNIZATION en
dc.subject.other FETAL ANEMIA en
dc.subject.other HEMORRHAGE en
dc.subject.other PREDICTION en
dc.subject.other MANAGEMENT en
dc.subject.other PREGNANCY en
dc.subject.other FETUSES en
dc.title Sonographic findings in severe fetomaternal transfusion en
heal.type journalArticle en
heal.language English en
heal.publicationDate 2010 en
heal.abstract Fetomaternal hemorrhage (FMH) or fetomaternal transfusion syndrome is the leakage of fetal red blood cells into the maternal circulation. Massive FMH can cause substantial fetal morbidity and mortality. Sonographic evidence of severe FMH syndrome includes fetal hydrops and other fetal anemia-related findings. The peak systolic velocity in the middle cerebral artery has extensively been used for the prediction of fetal anemia and for the timing of the first intrauterine intravascular transfusion (IIVT). We present a case of severe FMH syndrome that was diagnosed during the 24th week of pregnancy. A total of eight IIVT were performed. The actual increase in the fetal Hb after each transfusion was much lower than the expected. At 27 weeks of gestation, sonographic evaluation revealed areas of echogenicity around the posterior horns of the lateral ventricles suggesting ischemic damage. Due to these findings, no further IIVTs were offered and the fetus died a week later. The management of fetal anemia caused by severe FMH is difficult, and the anemic fetuses do not respond well to serial IIVTs as the transfer of blood to the maternal circulation continues. en
heal.publisher SPRINGER HEIDELBERG en
heal.journalName ARCHIVES OF GYNECOLOGY AND OBSTETRICS en
dc.identifier.isi ISI:000273081200010 en
dc.identifier.volume 281 en
dc.identifier.issue 2 en
dc.identifier.spage 241 en
dc.identifier.epage 245 en


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