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Enzymatic transformation of flavonoids and terpenoids: Structural and functional diversity of the novel derivatives

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dc.contributor.author Xanthakis, E en
dc.contributor.author Theodosiou, E en
dc.contributor.author Magkouta, S en
dc.contributor.author Stamatis, H en
dc.contributor.author Loutrari, H en
dc.contributor.author Roussos, C en
dc.contributor.author Kolisis, F en
dc.date.accessioned 2014-03-01T02:46:47Z
dc.date.available 2014-03-01T02:46:47Z
dc.date.issued 2010 en
dc.identifier.issn 0033-4545 en
dc.identifier.uri http://hdl.handle.net/123456789/32848
dc.subject Anti-tumoractivity en
dc.subject Biocatalysis en
dc.subject Flavonoids en
dc.subject Phytochemicals en
dc.subject Terpenoids en
dc.subject.classification Chemistry, Multidisciplinary en
dc.subject.other CANDIDA-ANTARCTICA LIPASE en
dc.subject.other POLYHYDROXYLATED NATURAL COMPOUNDS en
dc.subject.other REGIOSELECTIVE ACYLATION en
dc.subject.other IONIC LIQUIDS en
dc.subject.other PERILLYL ALCOHOL en
dc.subject.other PHENOLIC-ACIDS en
dc.subject.other FATTY-ACIDS en
dc.subject.other CATALYZED ESTERIFICATION en
dc.subject.other CHEMOENZYMATIC SYNTHESIS en
dc.subject.other BIOCATALYTIC PREPARATION en
dc.title Enzymatic transformation of flavonoids and terpenoids: Structural and functional diversity of the novel derivatives en
heal.type conferenceItem en
heal.identifier.primary 10.1351/PAC-CON-09-01-19 en
heal.identifier.secondary http://dx.doi.org/10.1351/PAC-CON-09-01-19 en
heal.language English en
heal.publicationDate 2010 en
heal.abstract Flavonoids and terpenoids are promising candidates for use as functional foods and novel therapeutics due to their prominent biological activities. However, the use of several bioactive plant compounds is limited by low stability and solubility problems. This review underlines the feasibility of enzymatic synthesis of novel bioactive analogs of selected flavonoids (silybin, rutin) and terpenoids (perillyl alcohol, POH) in nonconventional reaction systems. The effect of various parameters on the enzymatic acylation and/or glucosylation of these phytochemicals was studied. Also, the role of the structure of the novel molecules in relation to their biological function was investigated in various cancer cell lines. © 2010 IUPAC. en
heal.publisher INT UNION PURE APPLIED CHEMISTRY en
heal.journalName Pure and Applied Chemistry en
dc.identifier.doi 10.1351/PAC-CON-09-01-19 en
dc.identifier.isi ISI:000274709300002 en
dc.identifier.volume 82 en
dc.identifier.issue 1 en
dc.identifier.spage 1 en
dc.identifier.epage 16 en


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