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Atomic force microscopy imaging of the nanoscale assembly of type i collagen on controlled polystyrene particles surfaces

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dc.contributor.author Stylianou, A en
dc.contributor.author Politopoulos, K en
dc.contributor.author Yova, D en
dc.date.accessioned 2014-03-01T02:52:54Z
dc.date.available 2014-03-01T02:52:54Z
dc.date.issued 2011 en
dc.identifier.issn 16800737 en
dc.identifier.uri http://hdl.handle.net/123456789/36136
dc.subject Atomic Force Microscopy en
dc.subject Collagen en
dc.subject Nanobiomaterials en
dc.subject Polystyrene Particles en
dc.subject.other Annealing condition en
dc.subject.other Atomic force en
dc.subject.other Biomedical applications en
dc.subject.other Environmental conditions en
dc.subject.other Functionalized en
dc.subject.other High resolution en
dc.subject.other Nano pattern en
dc.subject.other Nano-scale organization en
dc.subject.other Nanobiomaterials en
dc.subject.other Nanoscale assemblies en
dc.subject.other Patterned surface en
dc.subject.other Polystyrene particle en
dc.subject.other Polystyrene Particles en
dc.subject.other Research areas en
dc.subject.other Solid surface en
dc.subject.other Tissue mechanics en
dc.subject.other Type I collagen en
dc.subject.other Adsorption en
dc.subject.other Atomic force microscopy en
dc.subject.other Biocompatibility en
dc.subject.other Collagen en
dc.subject.other Environmental regulations en
dc.subject.other Iodine en
dc.subject.other Medical applications en
dc.subject.other Medical imaging en
dc.subject.other Morphology en
dc.subject.other Nanostructured materials en
dc.subject.other Nanotechnology en
dc.subject.other Polystyrenes en
dc.subject.other Spinning (fibers) en
dc.subject.other Substrates en
dc.subject.other Tissue en
dc.subject.other Tissue engineering en
dc.subject.other Surfaces en
dc.title Atomic force microscopy imaging of the nanoscale assembly of type i collagen on controlled polystyrene particles surfaces en
heal.type conferenceItem en
heal.identifier.primary 10.1007/978-3-642-23508-5_275 en
heal.identifier.secondary http://dx.doi.org/10.1007/978-3-642-23508-5_275 en
heal.publicationDate 2011 en
heal.abstract The adsorption of collagen and the morphology of its assemblies at solid surfaces play an important role in a variety of research areas and applications, such as biomaterials, biocompatibility, tissue mechanics and cell studies. In this paper the nanoscale organization of type I collagen on polystyrene particle surfaces with controlled patterns was investigated by high-resolution atomic force microscopy. The results showed that patterned surfaces with a well-ordered morphology could be formed by spin coating polystyrene particles dispersions (20 sec at 1000 rpm) and appropriate annealing conditions (at 90°C for 2h). Collagen thin films consisting of fibers with natural characteristics, such as the typical 67nm periodicity (D-band), were formed on these nano-patterns. This kind of surfaces provides a useful substrate for studying the regulation of collagen assembly on substrates with different nano-topographical and environmental conditions and offers a potential way to create surfaces of functionalized and nano-patterend materials for biotechnological and biomedical applications. © 2011 Springer-Verlag Berlin Heidelberg. en
heal.journalName IFMBE Proceedings en
dc.identifier.doi 10.1007/978-3-642-23508-5_275 en
dc.identifier.volume 37 en
dc.identifier.spage 1058 en
dc.identifier.epage 1061 en


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