Synthesis and spectroscopic studies of optically active N-acetyl butenoates and N-acetyl-2-alkyl-pyrrolin-4-ones

Gavrielatos, E; Athanasellis, G; Igglessi-Markopoulou, O

dc.contributor.author	Gavrielatos, E	en
dc.contributor.author	Athanasellis, G	en
dc.contributor.author	Igglessi-Markopoulou, O	en
dc.date.accessioned	2014-03-01T01:18:23Z
dc.date.available	2014-03-01T01:18:23Z
dc.date.issued	2002	en
dc.identifier.issn	0022-152X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/14973
dc.subject	Optical Activity	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	ester	en
dc.subject.other	heterocyclic compound	en
dc.subject.other	ketone derivative	en
dc.subject.other	n acetyl butenoate	en
dc.subject.other	pyrroline derivative	en
dc.subject.other	unclassified drug	en
dc.subject.other	article	en
dc.subject.other	chirality	en
dc.subject.other	cyclization	en
dc.subject.other	enantiomer	en
dc.subject.other	high performance liquid chromatography	en
dc.subject.other	infrared spectrometry	en
dc.subject.other	spectroscopy	en
dc.subject.other	structure analysis	en
dc.subject.other	synthesis	en
dc.title	Synthesis and spectroscopic studies of optically active N-acetyl butenoates and N-acetyl-2-alkyl-pyrrolin-4-ones	en
heal.type	journalArticle	en
heal.identifier.primary	10.1002/jhet.5570390127	en
heal.identifier.secondary	http://dx.doi.org/10.1002/jhet.5570390127	en
heal.language	English	en
heal.publicationDate	2002	en
heal.abstract	The synthesis of a series of optically active N-acetyl butenoates 3-5 is described using a facile methodology. These butenoates undergo cyclization to the corresponding N-acetyl-2-alkyl-pyrrolin-4-ones 6,7 retaining their stereochemical integrity. The structure of the newly synthesized compounds has been elucidated through H-1-C-13 NMR, IR spectroscopy and their enantiomeric excesses have been measured by chiral HPLC analysis.	en
heal.publisher	HETERO CORPORATION	en
heal.journalName	Journal of Heterocyclic Chemistry	en
dc.identifier.doi	10.1002/jhet.5570390127	en
dc.identifier.isi	ISI:000174926800027	en
dc.identifier.volume	39	en
dc.identifier.issue	1	en
dc.identifier.spage	185	en
dc.identifier.epage	188	en