Alternatives to excimer laser refractive surgery: UV and mid-infrared laser ablation of intraocular lenses and porcine cornea

Serafetinides, AA; Makropoulou, M; Spyratou, E; Bacharis, C

dc.contributor.author	Serafetinides, AA	en
dc.contributor.author	Makropoulou, M	en
dc.contributor.author	Spyratou, E	en
dc.contributor.author	Bacharis, C	en
dc.date.accessioned	2014-03-01T02:51:02Z
dc.date.available	2014-03-01T02:51:02Z
dc.date.issued	2007	en
dc.identifier.issn	0277786X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/35313
dc.subject.other	Excimer lasers	en
dc.subject.other	Intraocular lenses	en
dc.subject.other	Laser ablation	en
dc.subject.other	Mathematical models	en
dc.subject.other	Ophthalmology	en
dc.subject.other	Optical microscopy	en
dc.subject.other	Solid state lasers	en
dc.subject.other	Excimer laser refractive surgery	en
dc.subject.other	Laser wavelengths	en
dc.subject.other	Optical penetration depth	en
dc.subject.other	Porcine cornea	en
dc.subject.other	Laser surgery	en
dc.title	Alternatives to excimer laser refractive surgery: UV and mid-infrared laser ablation of intraocular lenses and porcine cornea	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1117/12.727214	en
heal.identifier.secondary	http://dx.doi.org/10.1117/12.727214	en
heal.identifier.secondary	660427	en
heal.publicationDate	2007	en
heal.abstract	Despite the fact that the laser applications in human ophthalmology are well established, further research is still required, for better and predictable ablation dosimetry on both cornea tissue and intraocular lenses. Further studies for alternative laser sources to the well established excimer lasers, such as UV or mid-infrared solid state lasers, have been proposed for refractive surgery. The precise lens ablation requires the use of laser wavelengths possessing a small optical penetration depth in the cornea and in the synthetic lenses, in order to confine the laser energy deposition to a small volume. In order to eliminate some very well known problems concerning the reshaping of cornea and the modification of the optical properties of the intraocular lenses, ablation experiments of ex vivo porcine cornea, acrylic PMMA and hydrophilic lenses were conducted with an Er:YAG laser (2.94 μm) and the fifth harmonic of a Nd:YAG laser (213 nm). The morphology of cornea was recorded using a cornea topography system before and immediately after the ablation. Histology analysis of the specimens was obtained, in order to examine the microscopic appearance of the ablated craters and the existence of any thermal damage caused by the mid-infrared and UV laser irradiation. The macroscopic morphology of the intraocular lens craters was inspected with an optical transmission microscope. Measurements of the ablation rates of the lenses were performed and simulated by a mathematical model.	en
heal.journalName	Proceedings of SPIE - The International Society for Optical Engineering	en
dc.identifier.doi	10.1117/12.727214	en
dc.identifier.volume	6604	en