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Controlled release of newer quinolones from biodegradable systems based on poly(lactic acid)

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dc.contributor.author Andreopoulos, AG en
dc.date.accessioned 2014-03-01T01:10:53Z
dc.date.available 2014-03-01T01:10:53Z
dc.date.issued 1995 en
dc.identifier.issn 0885-3282 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/11477
dc.relation.uri http://www.scopus.com/inward/record.url?eid=2-s2.0-0029380345&partnerID=40&md5=346abbbc9dc7cbc3759cd65f7d7319fd en
dc.subject controlled release en
dc.subject biodegradable en
dc.subject quinolones en
dc.subject resomer en
dc.subject ofloxacin en
dc.subject pefloxacin en
dc.subject ciprofloxacin en
dc.subject.classification Engineering, Biomedical en
dc.subject.classification Materials Science, Biomaterials en
dc.subject.other Aromatic compounds en
dc.subject.other Biodegradation en
dc.subject.other Drug products en
dc.subject.other Microorganisms en
dc.subject.other Organic polymers en
dc.subject.other Biodegradable systems en
dc.subject.other Ciprofloxacin en
dc.subject.other Infection en
dc.subject.other Ofloxacin en
dc.subject.other Pefloxacin en
dc.subject.other Polylactic acid en
dc.subject.other Quinolones en
dc.subject.other Resomer en
dc.subject.other Controlled drug delivery en
dc.subject.other 4 quinolone derivative en
dc.subject.other antiinfective agent en
dc.subject.other lactic acid en
dc.subject.other lactic acid derivative en
dc.subject.other polylactic acid en
dc.subject.other polymer en
dc.subject.other article en
dc.subject.other artificial membrane en
dc.subject.other chemistry en
dc.subject.other delayed release formulation en
dc.subject.other drug delivery system en
dc.subject.other Escherichia coli en
dc.subject.other in vitro study en
dc.subject.other time en
dc.subject.other 4-Quinolones en
dc.subject.other Anti-Infective Agents en
dc.subject.other Delayed-Action Preparations en
dc.subject.other Drug Delivery Systems en
dc.subject.other Escherichia coli en
dc.subject.other Lactates en
dc.subject.other Lactic Acid en
dc.subject.other Membranes, Artificial en
dc.subject.other Polymers en
dc.subject.other Time Factors en
dc.title Controlled release of newer quinolones from biodegradable systems based on poly(lactic acid) en
heal.type journalArticle en
heal.language English en
heal.publicationDate 1995 en
heal.abstract The release of newer quinolones (such as pefloxacin, ofloxacin, and ciprofloxacin) from biodegradable poly(D,L lactic acid) has been investigated. The in vitro study showed that drug delivery takes place for about two months and a maximum in concentration was recorded after fifteen days. The release from poly(lactic acid) slabs seemed to give high drug doses that are adequate for the treatment of infections caused by common pathogens. en
heal.publisher Technomic Publ Co Inc, Lancaster, PA, United States en
heal.journalName Journal of Biomaterials Applications en
dc.identifier.isi ISI:A1995TQ68400006 en
dc.identifier.volume 10 en
dc.identifier.issue 2 en
dc.identifier.spage [d]163 en
dc.identifier.epage 170 en


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