Analysis of focusing of pulse modulated microwave signals inside a tissue medium

Nikita, KS; Uzunoglu, NK

dc.contributor.author	Nikita, KS	en
dc.contributor.author	Uzunoglu, NK	en
dc.date.accessioned	2014-03-01T01:11:41Z
dc.date.available	2014-03-01T01:11:41Z
dc.date.issued	1996	en
dc.identifier.issn	0018-9480	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/11780
dc.subject	Biological Tissue	en
dc.subject	Boundary Condition	en
dc.subject	Boundary Value Problem	en
dc.subject	Electric Field	en
dc.subject	Electromagnetic Field	en
dc.subject	High Frequency	en
dc.subject	Integral Equation	en
dc.subject	Normal Modes	en
dc.subject	Satisfiability	en
dc.subject	Wave Equation	en
dc.subject	Point of Interest	en
dc.subject	Time Dependent	en
dc.subject.classification	Engineering, Electrical & Electronic	en
dc.subject.other	DISPERSIVE MEDIA	en
dc.subject.other	PHASED-ARRAY	en
dc.subject.other	PROPAGATION	en
dc.subject.other	HYPERTHERMIA	en
dc.subject.other	RADIOTHERAPY	en
dc.subject.other	SYSTEMS	en
dc.title	Analysis of focusing of pulse modulated microwave signals inside a tissue medium	en
heal.type	journalArticle	en
heal.identifier.primary	10.1109/22.539936	en
heal.identifier.secondary	http://dx.doi.org/10.1109/22.539936	en
heal.language	English	en
heal.publicationDate	1996	en
heal.abstract	The possibility to achieve focusing in a three-layer cylindrical biological tissue model, by using a large number of concentrically placed waveguide applicators and pulsed signals (similar to 1 ns pulse width) with a high frequency (9.5 GHz) carrier is examined rigorously, The medium response to time harmonic excitation of the array is predicted, by solving the associated boundary value problem, To this end, the fields inside the tissue layers are expressed as integrals of vector cylindrical waves, satisfying the corresponding wave equations, while the fields inside the waveguides are expanded in terms of the guided and evanescent normal modes, By imposing the appropriate boundary conditions, a system of coupled integral equations is derived on the waveguide apertures, which is solved by expressing the unknown electric fields in terms of the waveguide modes and by applying a Galerkin procedure, Then, the medium response to pulse modulated excitation of the array elements is considered and the time dependence of the electromagnetic fields produced at any point within tissue is obtained in the form of an inverse Fourier integral. Numerical results are computed and presented at several points in a three-layer geometry, 20 cm in diameter, irradiated by a 30-element waveguide array and the use of time coincidence and constructive phase interference principles is examined, in order to achieve focusing at a specific point of interest within tissue.	en
heal.publisher	IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC	en
heal.journalName	IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES	en
dc.identifier.doi	10.1109/22.539936	en
dc.identifier.isi	ISI:A1996VM86200006	en
dc.identifier.volume	44	en
dc.identifier.issue	10	en
dc.identifier.spage	1788	en
dc.identifier.epage	1798	en