Investigation of the clustering processes occurring in liquid secondary ion mass spectrometry for alkyl quaternary ammonium bromides

Paul, GJC; Marcotte, I; Anastassopoulou, J; Theophanides, T; Arkas, M; Paleos, CM; Bertrand, MJ

dc.contributor.author	Paul, GJC	en
dc.contributor.author	Marcotte, I	en
dc.contributor.author	Anastassopoulou, J	en
dc.contributor.author	Theophanides, T	en
dc.contributor.author	Arkas, M	en
dc.contributor.author	Paleos, CM	en
dc.contributor.author	Bertrand, MJ	en
dc.date.accessioned	2014-03-01T01:12:02Z
dc.date.available	2014-03-01T01:12:02Z
dc.date.issued	1996	en
dc.identifier.issn	1076-5174	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/11923
dc.subject	Alkyl quaternary ammonium salts	en
dc.subject	Dimerization	en
dc.subject	Equilibrium	en
dc.subject	LSIMS	en
dc.subject	Relative bond strength	en
dc.subject.classification	Biophysics	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.classification	Spectroscopy	en
dc.subject.other	quaternary ammonium derivative	en
dc.subject.other	article	en
dc.subject.other	drug structure	en
dc.subject.other	electricity	en
dc.subject.other	mass spectrometry	en
dc.subject.other	nonhuman	en
dc.subject.other	priority journal	en
dc.subject.other	proprioception	en
dc.subject.other	technique	en
dc.title	Investigation of the clustering processes occurring in liquid secondary ion mass spectrometry for alkyl quaternary ammonium bromides	en
heal.type	journalArticle	en
heal.identifier.primary	10.1002/(SICI)1096-9888(199601)31:1<95::AID-JMS275>3.0.CO;2-V	en
heal.identifier.secondary	http://dx.doi.org/10.1002/(SICI)1096-9888(199601)31:1<95::AID-JMS275>3.0.CO;2-V	en
heal.language	English	en
heal.publicationDate	1996	en
heal.abstract	Upon investigation of the clustering behavior of a series of alkyl quaternary ammonium bromides (MBr) in liquid secondary ion mass spectrometry (LSIMS), only the dimer ion, M(2)Br(+), was of significant abundance in the resultant mass spectra. The ion abundance of the dimer grows relative to that of the molecular ion, M(+), with increasing analyte concentration in LSIMS until a concentration is reached where the ion abundance ratio M(2)Br(+)/M(+) remains constant upon subsequent analyte addition, The relationship between the M(2)Br(+)/M(+) ion abundance ratio and analyte concentration can be explained in terms of the solution equilibrium between these species, where the plateau region of the plot corresponds to the presence of an analyte monolayer at the liquid surface. The M(2)Br(+)/M(+) values obtained in this region provide relative dimer bond strengths for the alkyl quaternary ammonium salts, so the effect of different substituents on dimer stability can be assessed. Using this method, the importance of the electrostatic interaction on the dimer strength and the destabilizing effect of the hydrophobic interaction between long alkyl chains is revealed.	en
heal.publisher	JOHN WILEY & SONS LTD	en
heal.journalName	Journal of Mass Spectrometry	en
dc.identifier.doi	10.1002/(SICI)1096-9888(199601)31:1<95::AID-JMS275>3.0.CO;2-V	en
dc.identifier.isi	ISI:A1996TQ18800012	en
dc.identifier.volume	31	en
dc.identifier.issue	1	en
dc.identifier.spage	95	en
dc.identifier.epage	100	en