Reactions of N-hydroxysuccinimide esters of N-alkoxycarbonyl-α-amino acids with active methylene compounds. Synthesis of 3-substituted tetramic acids

Detsi, A; Markopoulos, J; Igglessi-Markopoulou, O

dc.contributor.author	Detsi, A	en
dc.contributor.author	Markopoulos, J	en
dc.contributor.author	Igglessi-Markopoulou, O	en
dc.date.accessioned	2014-03-01T01:12:13Z
dc.date.available	2014-03-01T01:12:13Z
dc.date.issued	1996	en
dc.identifier.issn	1359-7345	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/12017
dc.subject	Amino Acid	en
dc.subject.classification	Chemistry, Multidisciplinary	en
dc.subject.other	3-ACYLTETRAMIC ACIDS	en
dc.subject.other	ACYLAMINOACETYL DERIVATIVES	en
dc.subject.other	FULIGORUBIN-A	en
dc.subject.other	CYCLIZATION	en
dc.title	Reactions of N-hydroxysuccinimide esters of N-alkoxycarbonyl-α-amino acids with active methylene compounds. Synthesis of 3-substituted tetramic acids	en
heal.type	journalArticle	en
heal.identifier.primary	10.1039/cc9960001323	en
heal.identifier.secondary	http://dx.doi.org/10.1039/cc9960001323	en
heal.language	English	en
heal.publicationDate	1996	en
heal.abstract	The N-hydroxysuccinimide esters of N-alkoxycarbonyl-alpha-amino acids react with active methylene compounds (cyanoacetic esters,malonic and acyl acetic esters), under basic conditions, to produce 3-substituted N-alkoxycarbonyl tetramic acids; in the case of the N-hydroxysuccinimide esters derived from L-aminoacids, the corresponding optically active tetramic acids are obtained.	en
heal.publisher	ROYAL SOC CHEMISTRY	en
heal.journalName	Chemical Communications	en
dc.identifier.doi	10.1039/cc9960001323	en
dc.identifier.isi	ISI:A1996UR34700031	en
dc.identifier.issue	11	en
dc.identifier.spage	1323	en
dc.identifier.epage	1324	en