An efficient synthesis of novel N-acetyl-3-alkanoyl and 3-dienoyl tetramic acids

Petroliagi, M; Igglessi-Markopoulou, O

dc.contributor.author	Petroliagi, M	en
dc.contributor.author	Igglessi-Markopoulou, O	en
dc.date.accessioned	2014-03-01T01:12:37Z
dc.date.available	2014-03-01T01:12:37Z
dc.date.issued	1997	en
dc.identifier.issn	0300-922X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/12167
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	3-ACYLTETRAMIC ACIDS	en
dc.subject.other	N-ACETYL-3-BUTANOYLTETRAMIC ACID	en
dc.subject.other	TIRANDAMYCIN	en
dc.subject.other	COMPLEXES	en
dc.title	An efficient synthesis of novel N-acetyl-3-alkanoyl and 3-dienoyl tetramic acids	en
heal.type	journalArticle	en
heal.identifier.primary	10.1039/a702649h	en
heal.identifier.secondary	http://dx.doi.org/10.1039/a702649h	en
heal.language	English	en
heal.publicationDate	1997	en
heal.abstract	A general synthesis of N-acetyl-3-alkanoyl- and 3-dienoyl-tetramic acids is presented. The condensation of N-(N-acetylglycyloxy)succinimide with β-keto esters bearing alkanoyl or dienoyl groups furnishes the new 3-substituted N-acetyltetramic acids 6-9 and 16 in good yields. The key intermediates 4 and 5 have been isolated and subsequently cyclized to the corresponding tetramic acids. Spectral data for and the physical characteristics of all compounds are reported.	en
heal.publisher	ROYAL SOC CHEMISTRY	en
heal.journalName	Journal of the Chemical Society - Perkin Transactions 1	en
dc.identifier.doi	10.1039/a702649h	en
dc.identifier.isi	ISI:000071098700011	en
dc.identifier.issue	23	en
dc.identifier.spage	3543	en
dc.identifier.epage	3548	en