A conformal index (COIN) to evaluate implant quality and dose specification in brachytherapy

Baltas, D; Kolotas, C; Geramani, K; Mould, RF; Ioannidis, G; Kekchidi, M; Zamboglou, N

dc.contributor.author	Baltas, D	en
dc.contributor.author	Kolotas, C	en
dc.contributor.author	Geramani, K	en
dc.contributor.author	Mould, RF	en
dc.contributor.author	Ioannidis, G	en
dc.contributor.author	Kekchidi, M	en
dc.contributor.author	Zamboglou, N	en
dc.date.accessioned	2014-03-01T01:13:31Z
dc.date.available	2014-03-01T01:13:31Z
dc.date.issued	1998	en
dc.identifier.issn	0360-3016	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/12526
dc.subject	Conformal treatment	en
dc.subject	Dose-volume histogram	en
dc.subject	Interstitial brachytherapy	en
dc.subject	Quality index	en
dc.subject.classification	Oncology	en
dc.subject.classification	Radiology, Nuclear Medicine & Medical Imaging	en
dc.subject.other	article	en
dc.subject.other	cancer grading	en
dc.subject.other	cost benefit analysis	en
dc.subject.other	dose calculation	en
dc.subject.other	dosimetry	en
dc.subject.other	health care quality	en
dc.subject.other	interstitial radiation	en
dc.subject.other	priority journal	en
dc.subject.other	radiation dose	en
dc.subject.other	treatment planning	en
dc.subject.other	Algorithms	en
dc.subject.other	Brachytherapy	en
dc.subject.other	Catheters, Indwelling	en
dc.subject.other	Humans	en
dc.subject.other	Neoplasms	en
dc.subject.other	Radiotherapy Dosage	en
dc.subject.other	Radiotherapy Planning, Computer-Assisted	en
dc.subject.other	Tomography, X-Ray Computed	en
dc.title	A conformal index (COIN) to evaluate implant quality and dose specification in brachytherapy	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/S0360-3016(97)00732-3	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S0360-3016(97)00732-3	en
heal.language	English	en
heal.publicationDate	1998	en
heal.abstract	Purpose: To propose a new index (COIN) that can be easily understood and computed to assess high dose rate (HDR) brachytherapy interstitial implant quality and dose specification and is an improvement on existing indexes, Methods and Materials: The COIN index is based on an extension of dose-volume histograms and employs an analogous concept to that of cost-benefit analysis, which has already been applied to quality-of-life assessments for two alternative treatment protocols, The COIN index calculation methodology is shown for two cases: with and without critical structures. An analysis is given of dose distributions for two planning treatment volumes (PTV) of simple geometrical shape, applying both the rules of the Paris system and that of the "Offenbach" system. 40 patients who have received interstitial implants form the clinical material, With current HDR brachytherapy technology both for dose delivery, using remote afterloaders, and for three-dimensional (3D) treatment planning, it is now possible to relatively easily plan conformal brachytherapy treatments that would have been impossible with manual afterloading techniques and two-dimensional (2D) treatment planning, Results: Examples of the use of the COIN index are presented for experimental and clinical data, Conclusions: The results show that COIN is a useful and practical index to improve the quality of treatment of interstitial brachytherapy implants, Further work will be undertaken with a larger population of implanted cancer patients and a subdivision of the results by treatment site. (C) 1998 Elsevier Science Inc.	en
heal.publisher	PERGAMON-ELSEVIER SCIENCE LTD	en
heal.journalName	International Journal of Radiation Oncology Biology Physics	en
dc.identifier.doi	10.1016/S0360-3016(97)00732-3	en
dc.identifier.isi	ISI:000071662700035	en
dc.identifier.volume	40	en
dc.identifier.issue	2	en
dc.identifier.spage	515	en
dc.identifier.epage	524	en