A simplified simulation model and virtual reality visualization of tumour growth in vitro

Stamatakos, GS; Uzunoglu, NK; Delibasis, KK; Makropoulou, M; Mouravliansky, N; Marsh, A

dc.contributor.author	Stamatakos, GS	en
dc.contributor.author	Uzunoglu, NK	en
dc.contributor.author	Delibasis, KK	en
dc.contributor.author	Makropoulou, M	en
dc.contributor.author	Mouravliansky, N	en
dc.contributor.author	Marsh, A	en
dc.date.accessioned	2014-03-01T01:13:32Z
dc.date.available	2014-03-01T01:13:32Z
dc.date.issued	1998	en
dc.identifier.issn	0167-739X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/12552
dc.subject	Cancer	en
dc.subject	Simulation	en
dc.subject	Tumour growth modelling	en
dc.subject	Virtual reality	en
dc.subject	Visualization	en
dc.subject.classification	Computer Science, Theory & Methods	en
dc.subject.other	Cell culture	en
dc.subject.other	Computer simulation	en
dc.subject.other	Computer vision	en
dc.subject.other	Growth kinetics	en
dc.subject.other	Oncology	en
dc.subject.other	Three dimensional computer graphics	en
dc.subject.other	Virtual reality	en
dc.subject.other	Surface rendering	en
dc.subject.other	Volume rendering	en
dc.subject.other	Medical imaging	en
dc.title	A simplified simulation model and virtual reality visualization of tumour growth in vitro	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/S0167-739X(98)00011-9	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S0167-739X(98)00011-9	en
heal.language	English	en
heal.publicationDate	1998	en
heal.abstract	The aim of this paper is to demonstrate the impact that modern visualization techniques can have on the simulation of biological processes such as tumour growth. Therefore, a simplified three-dimensional cytokinetic simulation model of tumour growth in vitro has been developed. Results concerning the development of a small cell lung cancer (SCLC) tumour spheroid in cell culture have been obtained and their behaviour has been compared with both published data and laboratory experience. A special visualization system allowing real time surface and volume rendering on inexpensive computer hardware has been proposed. Its application to the model has led to a spectacular three-dimensional visualization of both the external and the internal structure of a growing tumour spheroid. (C) 1998 Elsevier Science B.V.	en
heal.publisher	ELSEVIER SCIENCE BV	en
heal.journalName	Future Generation Computer Systems	en
dc.identifier.doi	10.1016/S0167-739X(98)00011-9	en
dc.identifier.isi	ISI:000074480700008	en
dc.identifier.volume	14	en
dc.identifier.issue	1-2	en
dc.identifier.spage	79	en
dc.identifier.epage	89	en