Azocross-linked poly(acrylic acid) for colonic delivery and adhesion specificity: Synthesis and characterisation

Kakoulides, EP; Smart, JD; Tsibouklis, J

dc.contributor.author	Kakoulides, EP	en
dc.contributor.author	Smart, JD	en
dc.contributor.author	Tsibouklis, J	en
dc.date.accessioned	2014-03-01T01:13:36Z
dc.date.available	2014-03-01T01:13:36Z
dc.date.issued	1998	en
dc.identifier.issn	0168-3659	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/12603
dc.subject	4,4'-Divinylazobenzene	en
dc.subject	Azopolymers	en
dc.subject	Azoreduction	en
dc.subject	Biodegradable hydrogels	en
dc.subject	Colon-specific drug delivery	en
dc.subject	Mucoadhesion	en
dc.subject.classification	Chemistry, Multidisciplinary	en
dc.subject.classification	Pharmacology & Pharmacy	en
dc.subject.other	acrylic acid	en
dc.subject.other	benzene derivative	en
dc.subject.other	glatiramer	en
dc.subject.other	polyacrylic acid	en
dc.subject.other	article	en
dc.subject.other	colon	en
dc.subject.other	drug delivery system	en
dc.subject.other	hydrogel	en
dc.subject.other	infrared spectroscopy	en
dc.subject.other	nuclear magnetic resonance spectroscopy	en
dc.subject.other	polymerization	en
dc.subject.other	priority journal	en
dc.subject.other	reduction	en
dc.subject.other	Acrylic Resins	en
dc.subject.other	Azo Compounds	en
dc.subject.other	Colon	en
dc.subject.other	Drug Carriers	en
dc.subject.other	Intestinal Mucosa	en
dc.title	Azocross-linked poly(acrylic acid) for colonic delivery and adhesion specificity: Synthesis and characterisation	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/S0168-3659(98)00005-4	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S0168-3659(98)00005-4	en
heal.language	English	en
heal.publicationDate	1998	en
heal.abstract	A new synthetic pathway to 4,4'-divinylazobenzene is presented together with a procedure for the copolymerisation of this compound with acrylic acid. The chemical structure of the synthesised series of copolymers is examined in the light of infrared spectroscopy results and nuclear magnetic resonance data. The thermal properties of the materials are assessed using a combination of thermal analysis techniques and their swelling behaviour is evaluated at physiologically relevant buffers designed to mimic the gastrointestinal environment. (C) 1998 Elsevier Science B.V.	en
heal.publisher	ELSEVIER SCIENCE BV	en
heal.journalName	Journal of Controlled Release	en
dc.identifier.doi	10.1016/S0168-3659(98)00005-4	en
dc.identifier.isi	ISI:000072806100006	en
dc.identifier.volume	52	en
dc.identifier.issue	3	en
dc.identifier.spage	291	en
dc.identifier.epage	300	en