A new method for measuring red blood cell aggregation using pattern recognition techniques on backscattered ultrasound Doppler signals

Karabetsos, E; Papaodysseus, C; Koutsouris, D

dc.contributor.author	Karabetsos, E	en
dc.contributor.author	Papaodysseus, C	en
dc.contributor.author	Koutsouris, D	en
dc.date.accessioned	2014-03-01T01:14:20Z
dc.date.available	2014-03-01T01:14:20Z
dc.date.issued	1999	en
dc.identifier.issn	1386-0291	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/13000
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-0032957254&partnerID=40&md5=8f9e929fde474767d7b77b86641b341e	en
dc.subject	Erythrocyte aggregation	en
dc.subject	In vitro	en
dc.subject	Pattern recognition	en
dc.subject	PW Doppler ultrasound	en
dc.subject.classification	Hematology	en
dc.subject.classification	Peripheral Vascular Disease	en
dc.subject.other	article	en
dc.subject.other	diagnostic accuracy	en
dc.subject.other	diagnostic value	en
dc.subject.other	doppler flowmetry	en
dc.subject.other	erythrocyte aggregation	en
dc.subject.other	human	en
dc.subject.other	molecular weight	en
dc.subject.other	quantitative assay	en
dc.subject.other	signal processing	en
dc.subject.other	Erythrocyte Aggregation	en
dc.subject.other	Humans	en
dc.subject.other	Ultrasonography, Doppler	en
dc.title	A new method for measuring red blood cell aggregation using pattern recognition techniques on backscattered ultrasound Doppler signals	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	1999	en
heal.abstract	In order to study the important phenomenon of aggregation of red blood cell in vitro, an original ultrasound Doppler in vitro technique has been designed and developed in our laboratory. In the experiments held with this new technique, erythrocyte aggregation was examined by adding dextrans of different molecular weights and concentrations for a wide range of hematocrit values. Consequently, a large data base of backscattered ultrasound Doppler signals is created. In these signals, various pattern recognition methods have been applied, mainly morphological and statistical ones. It results from the employed analysis that the envelope, energy and area characteristics of the obtained backscattered signals are quite good indicators of the degree of RBCs aggregation. In this way, we have been able to: (a) Establish a quantitative relation between the presence of various dextrans and the degree of aggregation. (b) Determine the distribution of the size of the formed aggregates in the various experimental solutions. (c) Obtain a most accurate relation between ultrasound backscattering and actual size of the corresponding observed aggregates.	en
heal.publisher	IOS PRESS	en
heal.journalName	Clinical Hemorheology and Microcirculation	en
dc.identifier.isi	ISI:000080918400001	en
dc.identifier.volume	20	en
dc.identifier.issue	2	en
dc.identifier.spage	63	en
dc.identifier.epage	75	en