The role of free radical reactions with haemoglobin and thalassaemia

Anastassopoulou, J; Anifantakis, B; Anifantakis, ZA; Dovas, A; Theophanides, T

dc.contributor.author	Anastassopoulou, J	en
dc.contributor.author	Anifantakis, B	en
dc.contributor.author	Anifantakis, ZA	en
dc.contributor.author	Dovas, A	en
dc.contributor.author	Theophanides, T	en
dc.date.accessioned	2014-03-01T01:15:56Z
dc.date.available	2014-03-01T01:15:56Z
dc.date.issued	2000	en
dc.identifier.issn	0162-0134	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/13831
dc.subject	thalassaemia	en
dc.subject	ATP-Fe3+	en
dc.subject	AMP-Fe3+	en
dc.subject	free radicals	en
dc.subject	haemoglobin	en
dc.subject.classification	Biochemistry & Molecular Biology	en
dc.subject.classification	Chemistry, Inorganic & Nuclear	en
dc.subject.other	IRON CHELATORS	en
dc.subject.other	THALASSEMIA	en
dc.subject.other	SUPEROXIDE	en
dc.title	The role of free radical reactions with haemoglobin and thalassaemia	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/S0162-0134(99)00247-0	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S0162-0134(99)00247-0	en
heal.language	English	en
heal.publicationDate	2000	en
heal.abstract	It is well known that all living systems depend on iron to transport (haemoglobin), store (myoglobin) and utilize (cytochromes, cytochrome oxide) oxygen for respiration. Iron is an essential component in the active sites of the enzyme that protects against oxidation, such as the iron superoxide dismutase, in bacteria and plants. In normal human plasma almost all iron loading of transferrin is 20-30% maximum. In this presentation we review and summarize recent developments in our understanding of iron transport and storage in living systems. (C) 2000 Elsevier Science Inc. All rights reserved.	en
heal.publisher	ELSEVIER SCIENCE INC	en
heal.journalName	JOURNAL OF INORGANIC BIOCHEMISTRY	en
dc.identifier.doi	10.1016/S0162-0134(99)00247-0	en
dc.identifier.isi	ISI:000086988500047	en
dc.identifier.volume	79	en
dc.identifier.issue	1-4	en
dc.identifier.spage	327	en
dc.identifier.epage	329	en