Dosimetry close to an192Ir HDR source using N-vinylpyrrolidone based polymer gels and magnetic resonance imaging

Papagiannis, P; Pappas, E; Kipouros, P; Angelopoulos, A; Sakelliou, L; Baras, P; Karaiskos, P; Seimenis, I; Sandilos, P; Baltas, D

dc.contributor.author	Papagiannis, P	en
dc.contributor.author	Pappas, E	en
dc.contributor.author	Kipouros, P	en
dc.contributor.author	Angelopoulos, A	en
dc.contributor.author	Sakelliou, L	en
dc.contributor.author	Baras, P	en
dc.contributor.author	Karaiskos, P	en
dc.contributor.author	Seimenis, I	en
dc.contributor.author	Sandilos, P	en
dc.contributor.author	Baltas, D	en
dc.date.accessioned	2014-03-01T01:16:26Z
dc.date.available	2014-03-01T01:16:26Z
dc.date.issued	2001	en
dc.identifier.issn	00942405	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/14046
dc.subject	Brachytherapy	en
dc.subject	HDR	en
dc.subject	Intravascular	en
dc.subject	Monte Carlo	en
dc.subject	Polymer-MRI dosimetry	en
dc.subject.other	iridium 192	en
dc.subject.other	povidone	en
dc.subject.other	accuracy	en
dc.subject.other	anisotropy	en
dc.subject.other	article	en
dc.subject.other	brachytherapy	en
dc.subject.other	calibration	en
dc.subject.other	dosimetry	en
dc.subject.other	gel	en
dc.subject.other	interventional radiology	en
dc.subject.other	nuclear magnetic resonance imaging	en
dc.subject.other	priority journal	en
dc.subject.other	radiation dose distribution	en
dc.subject.other	radiation measurement	en
dc.subject.other	system analysis	en
dc.subject.other	treatment planning	en
dc.title	Dosimetry close to an192Ir HDR source using N-vinylpyrrolidone based polymer gels and magnetic resonance imaging	en
heal.type	journalArticle	en
heal.identifier.primary	10.1118/1.1382603	en
heal.identifier.secondary	http://dx.doi.org/10.1118/1.1382603	en
heal.publicationDate	2001	en
heal.abstract	In this work, the utilization of polymer gel-MRI dosimetry for measurements at distances relevant to clinical brachytherapy and intravascular applications [i.e., in the mm range, where steep three-dimensional (3-D) dose gradients exist] is investigated using N-vinylpyrrolidone-based gels. Transverse axis radial dose distributions, dose distributions parallel to the source axis, and 2-D dose distributions around the commonly used microSelectron192Ir HDR source are measured for single source dwell position irradiations. Experimental results are found in good agreement with verified Monte Carlo calculations, even for distances less than 3 mm from the source. The effect of various MRI parameters, such as slice thickness, slice mispositioning, and in-plane resolution, on the accuracy of the method is also investigated. Possible limitations of the method are discussed, and its' overall potential in brachytherapy dosimetry is evaluated. Experimental 2-D dose distributions for an intravascular application following the Paris irradiation protocol are compared to corresponding commercial treatment planning system calculations. Results suggest that polymer gel-MRI dosimetry is capable of experimentally verifying dose distributions in relevant clinical intravascular applications. © 2001 American Association of Physicists in Medicine.	en
heal.journalName	Medical Physics	en
dc.identifier.doi	10.1118/1.1382603	en
dc.identifier.volume	28	en
dc.identifier.issue	7	en
dc.identifier.spage	1416	en
dc.identifier.epage	1426	en