Monte Carlo dosimetry of the selectSeed 125I interstitial brachytherapy seed

Karaiskos, P; Papagiannis, P; Sakelliou, L; Anagnostopoulos, G; Baltas, D

dc.contributor.author	Karaiskos, P	en
dc.contributor.author	Papagiannis, P	en
dc.contributor.author	Sakelliou, L	en
dc.contributor.author	Anagnostopoulos, G	en
dc.contributor.author	Baltas, D	en
dc.date.accessioned	2014-03-01T01:16:46Z
dc.date.available	2014-03-01T01:16:46Z
dc.date.issued	2001	en
dc.identifier.issn	00942405	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/14211
dc.subject	6711	en
dc.subject	125I	en
dc.subject	Brachytherapy	en
dc.subject	Dosimetry	en
dc.subject	Monte Carlo	en
dc.subject	SelectSeed	en
dc.subject.other	iodine 125	en
dc.subject.other	anisotropy	en
dc.subject.other	article	en
dc.subject.other	brachytherapy	en
dc.subject.other	calculation	en
dc.subject.other	calibration	en
dc.subject.other	dosimetry	en
dc.subject.other	priority journal	en
dc.subject.other	prostate	en
dc.subject.other	radiation dose	en
dc.subject.other	radioactivity	en
dc.subject.other	standard	en
dc.subject.other	system analysis	en
dc.subject.other	Anisotropy	en
dc.subject.other	Brachytherapy	en
dc.subject.other	Calibration	en
dc.subject.other	Iodine Radioisotopes	en
dc.subject.other	Monte Carlo Method	en
dc.subject.other	Radiometry	en
dc.title	Monte Carlo dosimetry of the selectSeed 125I interstitial brachytherapy seed	en
heal.type	journalArticle	en
heal.identifier.primary	10.1118/1.1384460	en
heal.identifier.secondary	http://dx.doi.org/10.1118/1.1384460	en
heal.publicationDate	2001	en
heal.abstract	This work provides full dosimetric data for the new selectSeed 125I prostate seed source to be distributed by Nucletron B.V. The AAPM TG-43 dosimetric formalism and the new 1999 NIST air kerma strength calibration standard have been followed. Air kerma strength, dose rate constant, radial dose functions, anisotropy functions, and anisotropy factors were calculated using Monte Carlo simulation. Corresponding calculations were also performed for the commercially available 6711 seed source, which is of similar design, for reasons of comparison. The calculated dose rate constant of the selectSeed was 0.954±0.005 cGy h-1 U-1 compared to 0.953±0.005 cGy h-1 U-1 for the 6711 source design. The latter value for the 6711 source suggests that the correction factor proposed by NIST for conversion of dose rate constants to the new 1999 NIST calibration standard may be overestimated by 2-3%. Radial dose functions of the two sources were found in good agreement for radial distances up to 4 cm, the selectSeed being less penetrating at greater radial distances (∼4% at 10 cm). The selectSeed source presents similar anisotropy characteristics with the 6711 source design. For both source designs, a distance and polar angle dependent discontinuity of anisotropy function values was observed owing to the dose contribution of radioactivity distributed on the ends of the cylindrical source cores. Variation of dosimetric parameters with possible variation in radioactive silver halide coating thickness of the silver source core of the new source was also investigated. © 2001 American Association of Physicists in Medicine.	en
heal.journalName	Medical Physics	en
dc.identifier.doi	10.1118/1.1384460	en
dc.identifier.volume	28	en
dc.identifier.issue	8	en
dc.identifier.spage	1753	en
dc.identifier.epage	1760	en