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Texture analysis of fluorescence microscopic images of colonic tissue sections

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dc.contributor.author Atlamazoglou, V en
dc.contributor.author Yova, D en
dc.contributor.author Kavantzas, N en
dc.contributor.author Loukas, S en
dc.date.accessioned 2014-03-01T01:17:13Z
dc.date.available 2014-03-01T01:17:13Z
dc.date.issued 2001 en
dc.identifier.issn 0140-0118 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/14395
dc.relation.uri http://www.scopus.com/inward/record.url?eid=2-s2.0-0035044127&partnerID=40&md5=b0352b9652a738b15671ae1fd7139056 en
dc.relation.uri http://www.scopus.com/inward/record.url?eid=2-s2.0-0035044127&partnerID=40&md5=b0352b9652a738b15671ae1fd7139056 en
dc.subject Co-occurence matrix en
dc.subject Colon tissue sections en
dc.subject Fluorescence microscopy en
dc.subject Image analysis en
dc.subject Rhodamine derivatives en
dc.subject Texture analysis en
dc.subject.classification Computer Science, Interdisciplinary Applications en
dc.subject.classification Engineering, Biomedical en
dc.subject.classification Mathematical & Computational Biology en
dc.subject.classification Medical Informatics en
dc.subject.other Optical microscopy en
dc.subject.other Organic acids en
dc.subject.other Textures en
dc.subject.other Tissue en
dc.subject.other Fluorescence microscopy images en
dc.subject.other Medical imaging en
dc.subject.other boronic acid derivative en
dc.subject.other fluorescent dye en
dc.subject.other rhodamine B en
dc.subject.other article en
dc.subject.other calculation en
dc.subject.other classification en
dc.subject.other colon adenocarcinoma en
dc.subject.other colon mucosa en
dc.subject.other controlled study en
dc.subject.other decision making en
dc.subject.other device en
dc.subject.other diagnostic value en
dc.subject.other discriminant analysis en
dc.subject.other evaluation en
dc.subject.other fluorescence microscopy en
dc.subject.other human en
dc.subject.other human tissue en
dc.subject.other image analysis en
dc.subject.other mathematical computing en
dc.subject.other scoring system en
dc.subject.other staining en
dc.subject.other tissue section en
dc.subject.other Adenocarcinoma en
dc.subject.other Colon en
dc.subject.other Colonic Neoplasms en
dc.subject.other Humans en
dc.subject.other Image Processing, Computer-Assisted en
dc.subject.other Intestinal Mucosa en
dc.subject.other Microscopy, Fluorescence en
dc.title Texture analysis of fluorescence microscopic images of colonic tissue sections en
heal.type journalArticle en
heal.language English en
heal.publicationDate 2001 en
heal.abstract The aim of this study was to assess the potential of texture analysis for the characterization of fluorescence images from colonic tissue sections stained with a novel and selective fluoroprobe, Rhodamine B-phenylboronic acid. Fluorescence microscopy images of colonic healthy mucosa (n=35) and adenocarcinomas (n=35) were digitally captured and subjected to image texture analysis. Textural features derived from the grey level co-occurrence matrix were calculated. A modified version of the multiple discriminant analysis criterion was used to choose an appropriate subset of features. A minimum Mahalanobis distance, linear discriminant classifier and a simple evaluation 'score' method were used to classify image feature data into the two categories. A subset of four textural features was selected and used for the description and classification of each image field. They were found appropriate to correctly classify 95% of the images into the two classes, using two different classifiers. These features contained information about local homogeneity and grey level linear dependencies of the image. This study demonstrated that texture analysis techniques could provide valuable diagnostic decision support in a complex domain such as colorectal tissue. en
heal.publisher PETER PEREGRINUS LTD en
heal.journalName Medical and Biological Engineering and Computing en
dc.identifier.isi ISI:000168606000001 en
dc.identifier.volume 39 en
dc.identifier.issue 2 en
dc.identifier.spage 145 en
dc.identifier.epage 151 en


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