Arterial compliance is a main variable determining the effectiveness of intra-aortic balloon counterpulsation: Quantitative data from an in vitro study

Papaioannou, TG; Mathioulakis, DS; Nanas, JN; Tsangaris, SG; Stamatelopoulos, SF; Moulopoulos, SD

dc.contributor.author	Papaioannou, TG	en
dc.contributor.author	Mathioulakis, DS	en
dc.contributor.author	Nanas, JN	en
dc.contributor.author	Tsangaris, SG	en
dc.contributor.author	Stamatelopoulos, SF	en
dc.contributor.author	Moulopoulos, SD	en
dc.date.accessioned	2014-03-01T01:17:33Z
dc.date.available	2014-03-01T01:17:33Z
dc.date.issued	2002	en
dc.identifier.issn	1350-4533	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/14560
dc.subject	Assisted circulation	en
dc.subject	Counterpulsation	en
dc.subject	Mock circulation	en
dc.subject.classification	Engineering, Biomedical	en
dc.subject.other	Balloons	en
dc.subject.other	Hydraulic models	en
dc.subject.other	Performance	en
dc.subject.other	Heart rates	en
dc.subject.other	Biomedical engineering	en
dc.subject.other	aorta balloon	en
dc.subject.other	arterial pressure	en
dc.subject.other	artery compliance	en
dc.subject.other	artery resistance	en
dc.subject.other	article	en
dc.subject.other	counterpulsation	en
dc.subject.other	experimental model	en
dc.subject.other	heart assist device	en
dc.subject.other	heart left ventricle function	en
dc.subject.other	heart rate	en
dc.subject.other	heart ventricle enddiastolic pressure	en
dc.subject.other	priority journal	en
dc.subject.other	simulation	en
dc.subject.other	systemic circulation	en
dc.subject.other	systolic blood pressure	en
dc.subject.other	Aorta	en
dc.subject.other	Blood Pressure	en
dc.subject.other	Compliance	en
dc.subject.other	Elasticity	en
dc.subject.other	Equipment Failure Analysis	en
dc.subject.other	Heart	en
dc.subject.other	Heart Diseases	en
dc.subject.other	Heart Rate	en
dc.subject.other	Hemodynamic Processes	en
dc.subject.other	Humans	en
dc.subject.other	Intra-Aortic Balloon Pumping	en
dc.subject.other	Models, Cardiovascular	en
dc.subject.other	Predictive Value of Tests	en
dc.subject.other	Reproducibility of Results	en
dc.subject.other	Sensitivity and Specificity	en
dc.subject.other	Vascular Capacitance	en
dc.subject.other	Vascular Resistance	en
dc.subject.other	Ventricular Function, Left	en
dc.title	Arterial compliance is a main variable determining the effectiveness of intra-aortic balloon counterpulsation: Quantitative data from an in vitro study	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/S1350-4533(02)00013-9	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S1350-4533(02)00013-9	en
heal.language	English	en
heal.publicationDate	2002	en
heal.abstract	Quantitative data concerning the effect of arterial compliance (AC) on the effectiveness of intra-aortic balloon counterpulsation (IABC) are lacking. The main objective of this study was to investigate the relationship between AC and IABC performance. For this purpose we constructed a Windkessel, lumped-element, hydraulic model of the systemic circulation. The model consisted of a left ventricular assist device (LVAD), a compliance chamber, a peripheral resistor and two open reservoirs. Two Datascope Driving systems were used to operate the LVAD and intra-aortic balloon. We studied the effect of arterial compliance on the effectiveness of IABC at different levels of mean pressure (55, 75 and 95 mmHg) and heart rates (80, 100, 120 bpm). Three indices were used to evaluate IABC performance: the reduction of systolic and end-diastolic ""arterial"" pressure and the augmentation of diastolic pressure, induced by the IABC. A 22% decrease in AC (1.8-1.4 ml/mmHg) lead to a 30-40% increase in the indices of IABC performance, independently from pressure. In conclusion, arterial compliance significantly affects IABC efficacy and it could be considered as a further clinical criterion to decide IABC application. © 2002 IPEM. Published by Elsevier Science Ltd. All rights reserved.	en
heal.publisher	ELSEVIER SCI LTD	en
heal.journalName	Medical Engineering and Physics	en
dc.identifier.doi	10.1016/S1350-4533(02)00013-9	en
dc.identifier.isi	ISI:000175971100004	en
dc.identifier.volume	24	en
dc.identifier.issue	4	en
dc.identifier.spage	279	en
dc.identifier.epage	284	en