Changes of P300 elicited during a working memory test in individuals with depersonalization-derealization experiences

Papageorgiou, C; Ventouras, E; Uzunoglu, N; Rabavilas, A; Stefanis, C

dc.contributor.author	Papageorgiou, C	en
dc.contributor.author	Ventouras, E	en
dc.contributor.author	Uzunoglu, N	en
dc.contributor.author	Rabavilas, A	en
dc.contributor.author	Stefanis, C	en
dc.date.accessioned	2014-03-01T01:17:36Z
dc.date.available	2014-03-01T01:17:36Z
dc.date.issued	2002	en
dc.identifier.issn	0302-282X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/14584
dc.subject	Depersonalization-derealization	en
dc.subject	Event-related potentials	en
dc.subject	P300	en
dc.subject	Working memory	en
dc.subject.classification	Neurosciences	en
dc.subject.classification	Psychiatry	en
dc.subject.classification	Psychology	en
dc.subject.other	adult	en
dc.subject.other	age	en
dc.subject.other	anticipation	en
dc.subject.other	article	en
dc.subject.other	brain region	en
dc.subject.other	clinical article	en
dc.subject.other	cognition	en
dc.subject.other	controlled study	en
dc.subject.other	depersonalization	en
dc.subject.other	depersonalization derealization disorder	en
dc.subject.other	event related potential	en
dc.subject.other	experience	en
dc.subject.other	female	en
dc.subject.other	gender	en
dc.subject.other	human	en
dc.subject.other	intelligence test	en
dc.subject.other	male	en
dc.subject.other	mental performance	en
dc.subject.other	mental test	en
dc.subject.other	neurobiology	en
dc.subject.other	priority journal	en
dc.subject.other	questionnaire	en
dc.subject.other	self concept	en
dc.subject.other	socioeconomics	en
dc.subject.other	statistical significance	en
dc.subject.other	working memory	en
dc.subject.other	Adult	en
dc.subject.other	Attention	en
dc.subject.other	Depersonalization	en
dc.subject.other	Event-Related Potentials, P300	en
dc.subject.other	Female	en
dc.subject.other	Humans	en
dc.subject.other	Male	en
dc.subject.other	Memory, Short-Term	en
dc.subject.other	Self Concept	en
dc.subject.other	Wechsler Scales	en
dc.title	Changes of P300 elicited during a working memory test in individuals with depersonalization-derealization experiences	en
heal.type	journalArticle	en
heal.identifier.primary	10.1159/000065415	en
heal.identifier.secondary	http://dx.doi.org/10.1159/000065415	en
heal.language	English	en
heal.publicationDate	2002	en
heal.abstract	Background/Aim:The P300 component of Event-Related Potentials (ERPs) is related to fundamental aspects of cognitive functions, such as Working Memory (WM) and attention allocation. Deficits in these domains have been implicated in the pathophysiology of depersonalization-derealization (DID). The present study focused on the P300 elicited during a WM test in transient DID experiences. Methods: Fifteen subjects with transient DID experiences were matched for age, sex and educational level to an equal number of healthy controls. Both groups were submitted to a computerized version of the digit span Wechsler batteries. P300 Was measured during the anticipatory period of this test. All participants completed the Dixon self-rating questionnaire. Results: In relation to the control group, the subjects with transient DD experiences showed significantly decreased amplitudes of P300 at central posterior brain areas. Concerning memory performance, the groups did not differ significantly. Conclusions: These findings may indicate that subjects with transient DID experiences manifest altered aspects of information processing, as reflected by P300 amplitudes elicited during a WM test. Additionally, P300 might serve as a valuable investigative tool for a more comprehensive understanding of the neurobiological substrate of DID. Copyright (C) 2002 S. Karger AG, Basel.	en
heal.publisher	KARGER	en
heal.journalName	Neuropsychobiology	en
dc.identifier.doi	10.1159/000065415	en
dc.identifier.isi	ISI:000178706300004	en
dc.identifier.volume	46	en
dc.identifier.issue	2	en
dc.identifier.spage	70	en
dc.identifier.epage	75	en