Dosimetry comparison of 192Ir sources

Papagiannis, P; Angelopoulos, A; Pantelis, E; Sakelliou, L; Baltas, D; Karaiskos, P; Sandilos, P; Vlachos, L

dc.contributor.author	Papagiannis, P	en
dc.contributor.author	Angelopoulos, A	en
dc.contributor.author	Pantelis, E	en
dc.contributor.author	Sakelliou, L	en
dc.contributor.author	Baltas, D	en
dc.contributor.author	Karaiskos, P	en
dc.contributor.author	Sandilos, P	en
dc.contributor.author	Vlachos, L	en
dc.date.accessioned	2014-03-01T01:17:43Z
dc.date.available	2014-03-01T01:17:43Z
dc.date.issued	2002	en
dc.identifier.issn	0094-2405	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/14640
dc.subject	192Ir	en
dc.subject	Dosimetry	en
dc.subject	Intravascular	en
dc.subject	Monte Carlo	en
dc.subject.classification	Radiology, Nuclear Medicine & Medical Imaging	en
dc.subject.other	iridium 192	en
dc.subject.other	iridium	en
dc.subject.other	anisotropy	en
dc.subject.other	article	en
dc.subject.other	brachytherapy	en
dc.subject.other	dose calculation	en
dc.subject.other	dosimetry	en
dc.subject.other	geometry	en
dc.subject.other	mathematical analysis	en
dc.subject.other	Monte Carlo method	en
dc.subject.other	priority journal	en
dc.subject.other	radiation dose	en
dc.subject.other	instrumentation	en
dc.subject.other	methodology	en
dc.subject.other	photon	en
dc.subject.other	radiometry	en
dc.subject.other	Anisotropy	en
dc.subject.other	Brachytherapy	en
dc.subject.other	Iridium Radioisotopes	en
dc.subject.other	Monte Carlo Method	en
dc.subject.other	Photons	en
dc.subject.other	Radiometry	en
dc.title	Dosimetry comparison of 192Ir sources	en
heal.type	journalArticle	en
heal.identifier.primary	10.1118/1.1508378	en
heal.identifier.secondary	http://dx.doi.org/10.1118/1.1508378	en
heal.language	English	en
heal.publicationDate	2002	en
heal.abstract	Ir-192 sources besides being widely utilized in the field of conventional brachytherapy also find use in contemporary peripheral and coronal intravascular applications. In this study, the same Monte Carlo simulation code and input data were used to investigate differences between the dose rate distributions of the most commonly used Ir-192 sources in the cm and mm distance range. Findings are discussed in view of differences in source and encapsulation dimensions as well as structural details. Results are presented in the AAPM TG-43 formalism, as generalized by AAPM TG-60, for five Ir-192 HDR source designs as well as an LDR seed and an LDR wire source. Dose rate constants of the sources at r(0) = 1 cm and r(0) = 2 mm were found proportional to the corresponding geometry factors along the transverse source bisectors and an equation of the form Lambda(r0)(cGyh(-1) U-1) = 1.12 x G(r(0),90degrees) provides results within clinical accuracy (less than 2%) for any Ir-192 source. Radial dose functions do not depend significantly on source and encapsulation geometry and agree within 2% with that of a point Ir-192 source. Anisotropy is of importance for accurate dosimetry at the cm distance range but it does not affect dose rate in the mm, distance range significantly. At such short radial distances the source geometry factor defines the shape of isodose lines. Dose uniformity at given distances from the sources is strongly dependent on source dimensions as indicated by dose rate profiles in polar and Cartesian coordinates. (C) 2002 American Association of Physicists in Medicine.	en
heal.publisher	AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS	en
heal.journalName	Medical Physics	en
dc.identifier.doi	10.1118/1.1508378	en
dc.identifier.isi	ISI:000178646800006	en
dc.identifier.volume	29	en
dc.identifier.issue	10	en
dc.identifier.spage	2239	en
dc.identifier.epage	2246	en