Synthesis and characterization of low molecular weight polylactic acid

Proikakis, CS; Tarantili, PA; Andreopoulos, AG

dc.contributor.author	Proikakis, CS	en
dc.contributor.author	Tarantili, PA	en
dc.contributor.author	Andreopoulos, AG	en
dc.date.accessioned	2014-03-01T01:18:23Z
dc.date.available	2014-03-01T01:18:23Z
dc.date.issued	2002	en
dc.identifier.issn	0095-2443	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/14972
dc.subject	Biomedical applications	en
dc.subject	Lactic acid	en
dc.subject	Poly(lactic acid) oligomer	en
dc.subject	Polycondensation	en
dc.subject.classification	Materials Science, Multidisciplinary	en
dc.subject.classification	Polymer Science	en
dc.subject.other	Biomedical engineering	en
dc.subject.other	Characterization	en
dc.subject.other	Degradation	en
dc.subject.other	Distillation	en
dc.subject.other	Molecular weight	en
dc.subject.other	Polycondensation	en
dc.subject.other	Pyrolysis	en
dc.subject.other	Synthesis (chemical)	en
dc.subject.other	Xylene	en
dc.subject.other	Lactic acid	en
dc.subject.other	Polylactic acid	en
dc.subject.other	Oligomers	en
dc.title	Synthesis and characterization of low molecular weight polylactic acid	en
heal.type	journalArticle	en
heal.identifier.primary	10.1106/009524402021336	en
heal.identifier.secondary	http://dx.doi.org/10.1106/009524402021336	en
heal.language	English	en
heal.publicationDate	2002	en
heal.abstract	The polymerization of (D,L)-lactic acid in the absence of catalysts was studied. Azeotropic distillation using xylene, gave poly(lactic acid) with very low molecular weight, which however, was further increased by post-curing in an air oven. Moreover degradation phenomena and residual Xylene were observed, with this procedure. Polycondensation of lactic acid at temperatures up to 180degreesC under vacuum, resulted in fast reaction with poor control and the products are still characterized by low molecular weight. When the reaction was run at 220degreesC in inert atmosphere, amorphous poly(lactic acid) was obtained with molecular weight exceeding 3000. The product was found pure, since it is free from solvents, catalysts and monomer. Also, no evidence of thermal degradation was observed. The above characteristics are well acceptable design aspects for biomedical uses.	en
heal.publisher	SAGE PUBLICATIONS LTD	en
heal.journalName	Journal of Elastomers and Plastics	en
dc.identifier.doi	10.1106/009524402021336	en
dc.identifier.isi	ISI:000174626900003	en
dc.identifier.volume	34	en
dc.identifier.issue	1	en
dc.identifier.spage	49	en
dc.identifier.epage	63	en