Are dose calculations during dose optimization in brachytherapy necessary?

Lahanas, M; Baltas, D

dc.contributor.author	Lahanas, M	en
dc.contributor.author	Baltas, D	en
dc.date.accessioned	2014-03-01T01:18:41Z
dc.date.available	2014-03-01T01:18:41Z
dc.date.issued	2003	en
dc.identifier.issn	0094-2405	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/15154
dc.subject	Brachytherapy	en
dc.subject	Optimization algorithms	en
dc.subject.classification	Radiology, Nuclear Medicine & Medical Imaging	en
dc.subject.other	article	en
dc.subject.other	brachytherapy	en
dc.subject.other	calculation	en
dc.subject.other	dosimetry	en
dc.subject.other	mathematical computing	en
dc.subject.other	mathematical model	en
dc.subject.other	priority journal	en
dc.subject.other	technique	en
dc.subject.other	Algorithms	en
dc.subject.other	Brachytherapy	en
dc.subject.other	Computer Simulation	en
dc.subject.other	Dose Fractionation	en
dc.subject.other	Humans	en
dc.subject.other	Male	en
dc.subject.other	Models, Biological	en
dc.subject.other	Models, Statistical	en
dc.subject.other	Organ Specificity	en
dc.subject.other	Prostatic Neoplasms	en
dc.subject.other	Radiation Protection	en
dc.subject.other	Radiometry	en
dc.subject.other	Radiotherapy Dosage	en
dc.subject.other	Radiotherapy Planning, Computer-Assisted	en
dc.subject.other	Reproducibility of Results	en
dc.subject.other	Risk Assessment	en
dc.subject.other	Sample Size	en
dc.subject.other	Sensitivity and Specificity	en
dc.title	Are dose calculations during dose optimization in brachytherapy necessary?	en
heal.type	journalArticle	en
heal.identifier.primary	10.1118/1.1580483	en
heal.identifier.secondary	http://dx.doi.org/10.1118/1.1580483	en
heal.language	English	en
heal.publicationDate	2003	en
heal.abstract	We consider the problem of anatomy based dose optimization in brachytherapy. A calculation method for some objective functions and their derivatives is proposed which significantly reduces the number of required operations. The optimization in some cases, ignoring a preprocessing step, is independent of the number of sampling points. The idea is that some of the objectives and their derivatives used for dose optimization do not require the explicit calculation of dose values. Dose optimization with the new modified computation method for the objectives and derivatives is, depending on the number of sampling points, up to 100 times faster than the conventional method with dose calculation. (C) 2003 American Association of Physicists in Medicine.	en
heal.publisher	AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS	en
heal.journalName	Medical Physics	en
dc.identifier.doi	10.1118/1.1580483	en
dc.identifier.isi	ISI:000185379100014	en
dc.identifier.volume	30	en
dc.identifier.issue	9	en
dc.identifier.spage	2368	en
dc.identifier.epage	2375	en