In vivo thermoluminescence dosimetry dose verification of transperineal 192Ir high-dose-rate brachytherapy using CT-based planning for the treatment of prostate cancer

Anagnostopoulos, G; Baltas, D; Geretschlaeger, A; Martin, T; Papagiannis, P; Tselis, N; Zamboglou, N

dc.contributor.author	Anagnostopoulos, G	en
dc.contributor.author	Baltas, D	en
dc.contributor.author	Geretschlaeger, A	en
dc.contributor.author	Martin, T	en
dc.contributor.author	Papagiannis, P	en
dc.contributor.author	Tselis, N	en
dc.contributor.author	Zamboglou, N	en
dc.date.accessioned	2014-03-01T01:19:02Z
dc.date.available	2014-03-01T01:19:02Z
dc.date.issued	2003	en
dc.identifier.issn	0360-3016	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/15339
dc.subject	Brachytherapy	en
dc.subject	In vivo	en
dc.subject	Prostate	en
dc.subject	TLD	en
dc.subject.classification	Oncology	en
dc.subject.classification	Radiology, Nuclear Medicine & Medical Imaging	en
dc.subject.other	Catheters	en
dc.subject.other	Dosimetry	en
dc.subject.other	Oncology	en
dc.subject.other	Thermoluminescence	en
dc.subject.other	Tumors	en
dc.subject.other	Treatment planning systems	en
dc.subject.other	Radiotherapy	en
dc.subject.other	iridium 192	en
dc.subject.other	accuracy	en
dc.subject.other	analytical error	en
dc.subject.other	article	en
dc.subject.other	brachytherapy	en
dc.subject.other	catheter	en
dc.subject.other	clinical article	en
dc.subject.other	computer assisted tomography	en
dc.subject.other	human	en
dc.subject.other	male	en
dc.subject.other	priority journal	en
dc.subject.other	prostate cancer	en
dc.subject.other	radiation dose	en
dc.subject.other	thermoluminescence dosimetry	en
dc.subject.other	Brachytherapy	en
dc.subject.other	Calibration	en
dc.subject.other	Humans	en
dc.subject.other	Iridium Radioisotopes	en
dc.subject.other	Male	en
dc.subject.other	Prostatic Neoplasms	en
dc.subject.other	Radiotherapy Dosage	en
dc.subject.other	Radiotherapy Planning, Computer-Assisted	en
dc.subject.other	Thermoluminescent Dosimetry	en
dc.subject.other	Tomography, X-Ray Computed	en
dc.title	In vivo thermoluminescence dosimetry dose verification of transperineal 192Ir high-dose-rate brachytherapy using CT-based planning for the treatment of prostate cancer	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/S0360-3016(03)00762-4	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S0360-3016(03)00762-4	en
heal.language	English	en
heal.publicationDate	2003	en
heal.abstract	Purpose: To evaluate the potential of in vivo thermoluminescence dosimetry to estimate the accuracy of dose delivery in conformal high-dose-rate brachytherapy of prostate cancer. Methods and Materials: A total of 50 LiF, TLD-100 cylindrical rods were calibrated in the dose range of interest and used as a batch for all fractions. Fourteen dosimeters for every treatment fraction were loaded in a plastic 4F catheter that was fixed in either one of the 6F needles implanted for treatment purposes or in an extra needle implanted after consulting with the patient. The 6F needles were placed either close to the urethra or in the vicinity of the median posterior wall of the prostate. Initial results are presented for 18 treatment fractions in 5 patients and compared to corresponding data calculated using the commercial treatment planning system used for the planning of the treatments based on CT images acquired postimplantation. Results: The maximum observed mean difference between planned and delivered dose within a single treatment fraction was 8.57% +/- 2.61% (root mean square [RMS] errors from 4.03% to 9.73%). Corresponding values obtained after averaging results over all fractions of a patient were 6.88% +/- 4.93% (RMS errors from 4.82% to 7.32%). Experimental results of each fraction corresponding to the same patient point were found to agree within experimental uncertainties. Conclusions: Experimental results indicate that the proposed method is feasible for dose verification purposes and suggest that dose delivery in transperineal high-dose-rate brachytherapy after CT-based planning can be of acceptable accuracy. (C) 2003 Elsevier Inc.	en
heal.publisher	ELSEVIER SCIENCE INC	en
heal.journalName	International Journal of Radiation Oncology Biology Physics	en
dc.identifier.doi	10.1016/S0360-3016(03)00762-4	en
dc.identifier.isi	ISI:000186293800033	en
dc.identifier.volume	57	en
dc.identifier.issue	4	en
dc.identifier.spage	1183	en
dc.identifier.epage	1191	en