One Pot Synthesis of Methyl Aminoacetylcyanoacetates

Hamilakis, S; Tsolomitis, A

dc.contributor.author	Hamilakis, S	en
dc.contributor.author	Tsolomitis, A	en
dc.date.accessioned	2014-03-01T01:19:23Z
dc.date.available	2014-03-01T01:19:23Z
dc.date.issued	2003	en
dc.identifier.issn	0039-7911	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/15459
dc.subject	Aminoacetylcyanoacetates	en
dc.subject	C-Aminoacetylation	en
dc.subject	CDI	en
dc.subject	Enolimidazolinium salt	en
dc.subject	Imidazolides	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	acetic acid derivative	en
dc.subject.other	amino acid	en
dc.subject.other	aminoacetylcyanoacetate derivative	en
dc.subject.other	carbene	en
dc.subject.other	carbonyl derivative	en
dc.subject.other	carbonyl diimidazole	en
dc.subject.other	glycine derivative	en
dc.subject.other	imidazole derivative	en
dc.subject.other	methyl aminoacetylcyanoacetate derivative	en
dc.subject.other	methyl cyanoacetate	en
dc.subject.other	nitrile	en
dc.subject.other	unclassified drug	en
dc.subject.other	acylation	en
dc.subject.other	article	en
dc.subject.other	chemical analysis	en
dc.subject.other	chemical reaction	en
dc.subject.other	chemical structure	en
dc.subject.other	color	en
dc.subject.other	extraction	en
dc.subject.other	hydrogen bond	en
dc.subject.other	proton nuclear magnetic resonance	en
dc.subject.other	purification	en
dc.subject.other	reaction analysis	en
dc.subject.other	structure analysis	en
dc.subject.other	synthesis	en
dc.subject.other	technique	en
dc.title	One Pot Synthesis of Methyl Aminoacetylcyanoacetates	en
heal.type	journalArticle	en
heal.identifier.primary	10.1081/SCC-120026861	en
heal.identifier.secondary	http://dx.doi.org/10.1081/SCC-120026861	en
heal.language	English	en
heal.publicationDate	2003	en
heal.abstract	The C-acylation reactions of the methyl cyanoacetate with N-protected glycines by simultaneous activation of the amino acid carbonyl group and the methyl cyanoacetate methylene group using carbonyl diimidazole (CDI) have been here performed. The corresponding aminoacetylcyanoacetates were isolated (devoided of any impurities) as enols 4 in high yields, with a simple experimental, one pot, procedure.	en
heal.publisher	MARCEL DEKKER INC	en
heal.journalName	Synthetic Communications	en
dc.identifier.doi	10.1081/SCC-120026861	en
dc.identifier.isi	ISI:000187532900017	en
dc.identifier.volume	33	en
dc.identifier.issue	24	en
dc.identifier.spage	4313	en
dc.identifier.epage	4319	en