Performance evaluation of principal component analysis in dynamic FDG-PET studies of recurrent colorectal cancer

Thireou, T; Strauss, LG; Dimitrakopoulou-Strauss, A; Kontaxakis, G; Pavlopoulos, S; Santos, A

dc.contributor.author	Thireou, T	en
dc.contributor.author	Strauss, LG	en
dc.contributor.author	Dimitrakopoulou-Strauss, A	en
dc.contributor.author	Kontaxakis, G	en
dc.contributor.author	Pavlopoulos, S	en
dc.contributor.author	Santos, A	en
dc.date.accessioned	2014-03-01T01:19:25Z
dc.date.available	2014-03-01T01:19:25Z
dc.date.issued	2003	en
dc.identifier.issn	0895-6111	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/15478
dc.subject	Angiogenesis	en
dc.subject	Colorectal cancer	en
dc.subject	Dynamic positron emission tomography	en
dc.subject	Principal component analysis	en
dc.subject	Quantification	en
dc.subject	Treatment planning	en
dc.subject.classification	Radiology, Nuclear Medicine & Medical Imaging	en
dc.subject.other	Image reconstruction	en
dc.subject.other	Polynomials	en
dc.subject.other	Regression analysis	en
dc.subject.other	Tumors	en
dc.subject.other	Vessel density	en
dc.subject.other	Medical imaging	en
dc.subject.other	fluorodeoxyglucose f 18	en
dc.subject.other	accuracy	en
dc.subject.other	article	en
dc.subject.other	cancer diagnosis	en
dc.subject.other	cancer localization	en
dc.subject.other	clinical article	en
dc.subject.other	colorectal cancer	en
dc.subject.other	compartment model	en
dc.subject.other	controlled study	en
dc.subject.other	correlation analysis	en
dc.subject.other	correlation coefficient	en
dc.subject.other	correlation function	en
dc.subject.other	data analysis	en
dc.subject.other	density	en
dc.subject.other	evaluation	en
dc.subject.other	human	en
dc.subject.other	image analysis	en
dc.subject.other	metastasis	en
dc.subject.other	parameter	en
dc.subject.other	positron emission tomography	en
dc.subject.other	principal component analysis	en
dc.subject.other	priority journal	en
dc.subject.other	quantitative analysis	en
dc.subject.other	recurrent cancer	en
dc.subject.other	regression analysis	en
dc.subject.other	statistical analysis	en
dc.subject.other	tumor	en
dc.subject.other	tumor vascularization	en
dc.subject.other	vessel	en
dc.subject.other	Colorectal Neoplasms	en
dc.subject.other	Data Interpretation, Statistical	en
dc.subject.other	Fluorodeoxyglucose F18	en
dc.subject.other	Humans	en
dc.subject.other	Image Processing, Computer-Assisted	en
dc.subject.other	Neoplasm Recurrence, Local	en
dc.subject.other	Radiopharmaceuticals	en
dc.subject.other	Tomography, Emission-Computed	en
dc.title	Performance evaluation of principal component analysis in dynamic FDG-PET studies of recurrent colorectal cancer	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/S0895-6111(02)00050-2	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S0895-6111(02)00050-2	en
heal.language	English	en
heal.publicationDate	2003	en
heal.abstract	Performance evaluation of principal component analysis (PCA) of dynamic F-18-FDG-PET studies of patients with recurrent colorectal cancer. Principal component images (PCI) of 17 iteratively reconstructed data sets were visually and quantitatively evaluated. The F-18-FDG compartment model parameters were estimated using polynomial regression. All structures were present in PCIl. PCI2 was correlated with the vascular component and PCI3 with the tumor. The vessel density in the tumor was estimated with a correlation coefficient equal to 0.834. PCA supports the visual interpretation of dynamic F-18-FDG-PET studies, facilitates the application of compartment modeling and is a promising quantification technique. (C) 2002 Elsevier Science Ltd. All rights reserved.	en
heal.publisher	PERGAMON-ELSEVIER SCIENCE LTD	en
heal.journalName	Computerized Medical Imaging and Graphics	en
dc.identifier.doi	10.1016/S0895-6111(02)00050-2	en
dc.identifier.isi	ISI:000182469900007	en
dc.identifier.volume	27	en
dc.identifier.issue	1	en
dc.identifier.spage	43	en
dc.identifier.epage	51	en