Stability of DL-poly(lactic acid) in aqueous solutions

Proikakis, CS; Mamouzelos, NJ; Tarantili, PA; Andreopoulos, AG

dc.contributor.author	Proikakis, CS	en
dc.contributor.author	Mamouzelos, NJ	en
dc.contributor.author	Tarantili, PA	en
dc.contributor.author	Andreopoulos, AG	en
dc.date.accessioned	2014-03-01T01:19:33Z
dc.date.available	2014-03-01T01:19:33Z
dc.date.issued	2003	en
dc.identifier.issn	0021-8995	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/15572
dc.subject	Biodegradable	en
dc.subject	Drug delivery systems	en
dc.subject	Polyesters	en
dc.subject	Swelling	en
dc.subject.classification	Polymer Science	en
dc.subject.other	Bacteria	en
dc.subject.other	Biodegradation	en
dc.subject.other	Drug products	en
dc.subject.other	Formaldehyde	en
dc.subject.other	Functions	en
dc.subject.other	Hydrolysis	en
dc.subject.other	Infrared spectroscopy	en
dc.subject.other	Light scattering	en
dc.subject.other	Molecular weight	en
dc.subject.other	Nuclear magnetic resonance	en
dc.subject.other	Polycondensation	en
dc.subject.other	Polyesters	en
dc.subject.other	Solutions	en
dc.subject.other	Swelling	en
dc.subject.other	Viscosity measurement	en
dc.subject.other	Buffer solutions	en
dc.subject.other	Organic acids	en
dc.subject.other	medical application	en
dc.subject.other	swelling	en
dc.title	Stability of DL-poly(lactic acid) in aqueous solutions	en
heal.type	journalArticle	en
heal.identifier.primary	10.1002/app.11449	en
heal.identifier.secondary	http://dx.doi.org/10.1002/app.11449	en
heal.language	English	en
heal.publicationDate	2003	en
heal.abstract	DL-poly(lactic acid) of molecular weight about 2500 was prepared by polycondensation of lactic acid and characterized by viscosimetry, infrared spectroscopy, light scattering, GPC, and NMR. Tablets made of the above polymer were immersed in buffer solutions at 37°C, and their swelling behavior was recorded as a function of time, in terms of weight gain. In the same experiments, the hydrolytic stability of PLA was assessed by measuring the weight loss after drying the tablets. To inhibit any degradation due to bacteria, formaldehyde was added to the solution as a biostatic factor. © 2002 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 87.	en
heal.publisher	JOHN WILEY & SONS INC	en
heal.journalName	Journal of Applied Polymer Science	en
dc.identifier.doi	10.1002/app.11449	en
dc.identifier.isi	ISI:000179735700010	en
dc.identifier.volume	87	en
dc.identifier.issue	5	en
dc.identifier.spage	795	en
dc.identifier.epage	804	en