Free radical scavenging and antioxidant activity of 5,7,3′,4′-hydroxy-substituted flavonoids

Tsimogiannis, DI; Oreopoulou, V

dc.contributor.author	Tsimogiannis, DI	en
dc.contributor.author	Oreopoulou, V	en
dc.date.accessioned	2014-03-01T01:20:32Z
dc.date.available	2014-03-01T01:20:32Z
dc.date.issued	2004	en
dc.identifier.issn	14668564	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/15953
dc.subject	Antioxidants	en
dc.subject	DPPH	en
dc.subject	Flavonoids	en
dc.subject	Lipid peroxidation	en
dc.subject.other	Antioxidants	en
dc.subject.other	Catalyst activity	en
dc.subject.other	Chemical bonds	en
dc.subject.other	Composition effects	en
dc.subject.other	Free radical reactions	en
dc.subject.other	Lipids	en
dc.subject.other	Materials testing	en
dc.subject.other	Oils and fats	en
dc.subject.other	Organic solvents	en
dc.subject.other	Oxidation	en
dc.subject.other	Structure (composition)	en
dc.subject.other	Substitution reactions	en
dc.subject.other	Antioxidant activity	en
dc.subject.other	Free radical scavenging	en
dc.subject.other	Hydroxy-substituted flavonoids	en
dc.subject.other	Lipid peroxidation	en
dc.subject.other	Structural element contribution	en
dc.subject.other	Enzymes	en
dc.subject.other	1,1 diphenyl 2 picrylhydrazyl	en
dc.subject.other	acetic acid ethyl ester	en
dc.subject.other	carbon	en
dc.subject.other	carbonyl derivative	en
dc.subject.other	catechin	en
dc.subject.other	cotton seed oil	en
dc.subject.other	eriodictyol	en
dc.subject.other	flavonoid	en
dc.subject.other	free radical	en
dc.subject.other	lipid	en
dc.subject.other	luteolin	en
dc.subject.other	methanol	en
dc.subject.other	peroxide	en
dc.subject.other	quercetin	en
dc.subject.other	solvent	en
dc.subject.other	taxifolin	en
dc.subject.other	analytic method	en
dc.subject.other	analytical parameters	en
dc.subject.other	antioxidant activity	en
dc.subject.other	article	en
dc.subject.other	chemical bond	en
dc.subject.other	concentration response	en
dc.subject.other	controlled study	en
dc.subject.other	drug mechanism	en
dc.subject.other	lipid peroxidation	en
dc.subject.other	prediction	en
dc.subject.other	reaction analysis	en
dc.subject.other	satisfaction	en
dc.subject.other	scavenging system	en
dc.subject.other	statistical significance	en
dc.subject.other	structure activity relation	en
dc.subject.other	Micropus	en
dc.title	Free radical scavenging and antioxidant activity of 5,7,3′,4′-hydroxy-substituted flavonoids	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.ifset.2004.05.006	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.ifset.2004.05.006	en
heal.publicationDate	2004	en
heal.abstract	The antioxidant efficiencies of 5,7,3′,4′-hydroxy-substituted flavonoids were examined. The tested compounds (quercetin, luteolin, taxifolin, (+)-catechin and eriodictyol) were selected with a view to their C-ring differentiated pattern. Each one was added in cottonseed oil at equimolar amounts and the retardation of lipid peroxidation was estimated by means of peroxide value. Furthermore, their ability to scavenge DPPH radical was studied in two solvents (methanol and ethyl acetate) and the DPPH method proved a satisfactory prediction test for the antioxidant action of flavonoids in oils when methanol was used as the reaction media. Furthermore, the comparison of the C-ring structural element contribution to the antioxidant action revealed the full substitution to be the most important followed by the 3-OH and 2,3-double bond in the presence of the 4-carbonyl. Concerning the monosubstituted flavonoids, the 4-carbonyl group induced minor activity, whereas the 3-OH increased significantly the antiradical and antioxidant action. © 2004 Elsevier Ltd. All rights reserved.	en
heal.journalName	Innovative Food Science and Emerging Technologies	en
dc.identifier.doi	10.1016/j.ifset.2004.05.006	en
dc.identifier.volume	5	en
dc.identifier.issue	4	en
dc.identifier.spage	523	en
dc.identifier.epage	528	en