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Free radical scavenging and antioxidant activity of 5,7,3′,4′-hydroxy-substituted flavonoids

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dc.contributor.author Tsimogiannis, DI en
dc.contributor.author Oreopoulou, V en
dc.date.accessioned 2014-03-01T01:20:32Z
dc.date.available 2014-03-01T01:20:32Z
dc.date.issued 2004 en
dc.identifier.issn 14668564 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/15953
dc.subject Antioxidants en
dc.subject DPPH en
dc.subject Flavonoids en
dc.subject Lipid peroxidation en
dc.subject.other Antioxidants en
dc.subject.other Catalyst activity en
dc.subject.other Chemical bonds en
dc.subject.other Composition effects en
dc.subject.other Free radical reactions en
dc.subject.other Lipids en
dc.subject.other Materials testing en
dc.subject.other Oils and fats en
dc.subject.other Organic solvents en
dc.subject.other Oxidation en
dc.subject.other Structure (composition) en
dc.subject.other Substitution reactions en
dc.subject.other Antioxidant activity en
dc.subject.other Free radical scavenging en
dc.subject.other Hydroxy-substituted flavonoids en
dc.subject.other Lipid peroxidation en
dc.subject.other Structural element contribution en
dc.subject.other Enzymes en
dc.subject.other 1,1 diphenyl 2 picrylhydrazyl en
dc.subject.other acetic acid ethyl ester en
dc.subject.other carbon en
dc.subject.other carbonyl derivative en
dc.subject.other catechin en
dc.subject.other cotton seed oil en
dc.subject.other eriodictyol en
dc.subject.other flavonoid en
dc.subject.other free radical en
dc.subject.other lipid en
dc.subject.other luteolin en
dc.subject.other methanol en
dc.subject.other peroxide en
dc.subject.other quercetin en
dc.subject.other solvent en
dc.subject.other taxifolin en
dc.subject.other analytic method en
dc.subject.other analytical parameters en
dc.subject.other antioxidant activity en
dc.subject.other article en
dc.subject.other chemical bond en
dc.subject.other concentration response en
dc.subject.other controlled study en
dc.subject.other drug mechanism en
dc.subject.other lipid peroxidation en
dc.subject.other prediction en
dc.subject.other reaction analysis en
dc.subject.other satisfaction en
dc.subject.other scavenging system en
dc.subject.other statistical significance en
dc.subject.other structure activity relation en
dc.subject.other Micropus en
dc.title Free radical scavenging and antioxidant activity of 5,7,3′,4′-hydroxy-substituted flavonoids en
heal.type journalArticle en
heal.identifier.primary 10.1016/j.ifset.2004.05.006 en
heal.identifier.secondary http://dx.doi.org/10.1016/j.ifset.2004.05.006 en
heal.publicationDate 2004 en
heal.abstract The antioxidant efficiencies of 5,7,3′,4′-hydroxy-substituted flavonoids were examined. The tested compounds (quercetin, luteolin, taxifolin, (+)-catechin and eriodictyol) were selected with a view to their C-ring differentiated pattern. Each one was added in cottonseed oil at equimolar amounts and the retardation of lipid peroxidation was estimated by means of peroxide value. Furthermore, their ability to scavenge DPPH radical was studied in two solvents (methanol and ethyl acetate) and the DPPH method proved a satisfactory prediction test for the antioxidant action of flavonoids in oils when methanol was used as the reaction media. Furthermore, the comparison of the C-ring structural element contribution to the antioxidant action revealed the full substitution to be the most important followed by the 3-OH and 2,3-double bond in the presence of the 4-carbonyl. Concerning the monosubstituted flavonoids, the 4-carbonyl group induced minor activity, whereas the 3-OH increased significantly the antiradical and antioxidant action. © 2004 Elsevier Ltd. All rights reserved. en
heal.journalName Innovative Food Science and Emerging Technologies en
dc.identifier.doi 10.1016/j.ifset.2004.05.006 en
dc.identifier.volume 5 en
dc.identifier.issue 4 en
dc.identifier.spage 523 en
dc.identifier.epage 528 en


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