Psychophysiological correlates of patients with delusional misidentification syndromes and psychotic major depression

Papageorgiou, CC; Alevizos, B; Ventouras, E; Kontopantelis, E; Uzunoglu, N; Christodoulou, G

dc.contributor.author	Papageorgiou, CC	en
dc.contributor.author	Alevizos, B	en
dc.contributor.author	Ventouras, E	en
dc.contributor.author	Kontopantelis, E	en
dc.contributor.author	Uzunoglu, N	en
dc.contributor.author	Christodoulou, G	en
dc.date.accessioned	2014-03-01T01:21:16Z
dc.date.available	2014-03-01T01:21:16Z
dc.date.issued	2004	en
dc.identifier.issn	0165-0327	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/16171
dc.subject	Delusional misidentification syndromes (DMS)	en
dc.subject	Event-related potentials (ERPs)	en
dc.subject	P300	en
dc.subject	Psychotic major depression (PMD)	en
dc.subject	Working memory (WM)	en
dc.subject.classification	Clinical Neurology	en
dc.subject.classification	Psychiatry	en
dc.subject.other	adult	en
dc.subject.other	age	en
dc.subject.other	amplitude modulation	en
dc.subject.other	article	en
dc.subject.other	attenuation	en
dc.subject.other	brain dysfunction	en
dc.subject.other	brain function	en
dc.subject.other	brain region	en
dc.subject.other	controlled study	en
dc.subject.other	correlation analysis	en
dc.subject.other	delusional misidentification	en
dc.subject.other	depressive psychosis	en
dc.subject.other	female	en
dc.subject.other	frontal cortex	en
dc.subject.other	hemisphere	en
dc.subject.other	human	en
dc.subject.other	hypothesis	en
dc.subject.other	latent period	en
dc.subject.other	major depression	en
dc.subject.other	male	en
dc.subject.other	parietal lobe	en
dc.subject.other	priority journal	en
dc.subject.other	psychology	en
dc.subject.other	psychophysiology	en
dc.subject.other	sample size	en
dc.subject.other	sex	en
dc.subject.other	socioeconomics	en
dc.subject.other	Adult	en
dc.subject.other	Affective Disorders, Psychotic	en
dc.subject.other	Case-Control Studies	en
dc.subject.other	Delusions	en
dc.subject.other	Depressive Disorder	en
dc.subject.other	Event-Related Potentials, P300	en
dc.subject.other	Female	en
dc.subject.other	Humans	en
dc.subject.other	Male	en
dc.subject.other	Syndrome	en
dc.title	Psychophysiological correlates of patients with delusional misidentification syndromes and psychotic major depression	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/S0165-0327(03)00136-8	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S0165-0327(03)00136-8	en
heal.language	English	en
heal.publicationDate	2004	en
heal.abstract	Background: Psychotic major depression (PMD) and delusional misidentification syndromes (DMS) exhibit cognitive deficits. Since the P300 component of event-related potentials (ERPs) provides valuable information concerning cognition, we studied this component of ERPs in DMS and PMD patients. Methods: Nine patients with DMS, 15 patients with PMD, and 11 healthy controls, matched for age, sex and educational level, were tested using the auditory P300 component of ERPs. Results: Both patient groups showed significant reductions in P300 amplitude at the right frontal region, while DMS group showed significant attenuation of the P300 amplitude at the right parietal area. P300 latency was significantly prolonged in the central midline brain region in the DMS group. Limitations: The smallness of the sample size and the hypothetical post-hoc assignation of psychological function to regional activation. Conclusion: PMD and DMS patients may share similar psychophysiological alterations connected to the right frontal region, mediating automatic processes, while DMS are associated with dysfunction of effortful mechanisms and allocation of attentional resources involving the interhemispheric and right parietal circuitry. (C) 2003 Elsevier B.V. All rights reserved.	en
heal.publisher	ELSEVIER SCIENCE BV	en
heal.journalName	Journal of Affective Disorders	en
dc.identifier.doi	10.1016/S0165-0327(03)00136-8	en
dc.identifier.isi	ISI:000223646000007	en
dc.identifier.volume	81	en
dc.identifier.issue	2	en
dc.identifier.spage	147	en
dc.identifier.epage	152	en