A traceless solid-phase approach to functionalized tetramic acids and 2-amino-4-pyrrolinones

Prousis, KC; Detsi, A; Igglessi-Markopoulou, O

dc.contributor.author	Prousis, KC	en
dc.contributor.author	Detsi, A	en
dc.contributor.author	Igglessi-Markopoulou, O	en
dc.date.accessioned	2014-03-01T01:21:47Z
dc.date.available	2014-03-01T01:21:47Z
dc.date.issued	2005	en
dc.identifier.issn	0936-5214	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/16371
dc.subject	2-amino-4-pyrrolinones	en
dc.subject	Carbamate resin	en
dc.subject	Solid-phase synthesis	en
dc.subject	Tetramic acids	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	4 nitrophenyl carbonate	en
dc.subject.other	alpha amino acid	en
dc.subject.other	carbonic acid derivative	en
dc.subject.other	carboxyl group	en
dc.subject.other	pyrroline derivative	en
dc.subject.other	resin	en
dc.subject.other	tetramic acid derivative	en
dc.subject.other	unclassified drug	en
dc.subject.other	amino terminal sequence	en
dc.subject.other	article	en
dc.subject.other	commercial phenomena	en
dc.subject.other	methodology	en
dc.subject.other	quantum yield	en
dc.subject.other	solid	en
dc.subject.other	synthesis	en
dc.title	A traceless solid-phase approach to functionalized tetramic acids and 2-amino-4-pyrrolinones	en
heal.type	journalArticle	en
heal.identifier.primary	10.1055/s-2005-918941	en
heal.identifier.secondary	http://dx.doi.org/10.1055/s-2005-918941	en
heal.identifier.secondary	G16105ST	en
heal.language	English	en
heal.publicationDate	2005	en
heal.abstract	A novel traceless route for the synthesis of optically active functionalized tetramic acids and 2-amino-4-pyrrolinones on solid support is described. p-Nitrophenyl carbonate linker on Wang resin is used to anchor L-α-Amino acids by their N-terminus thus leaving the carboxylic function free for further elaboration. High yields and ee, in combination with the versatility implied by the wide range of commercially available building blocks, are the major advantages of the proposed methodology. © Georg Thieme Verlag Stuttgart.	en
heal.publisher	GEORG THIEME VERLAG KG	en
heal.journalName	Synlett	en
dc.identifier.doi	10.1055/s-2005-918941	en
dc.identifier.isi	ISI:000233175500011	en
dc.identifier.issue	18	en
dc.identifier.spage	2763	en
dc.identifier.epage	2766	en