Feasibility study of the use of similarity maps in the evaluation of oncological dynamic positron emission tomography images

Thireou, T; Kontaxakis, G; Strauss, LG; Dimitrakopoulou-Strauss, A; Pavlopoulos, S; Santos, A

dc.contributor.author	Thireou, T	en
dc.contributor.author	Kontaxakis, G	en
dc.contributor.author	Strauss, LG	en
dc.contributor.author	Dimitrakopoulou-Strauss, A	en
dc.contributor.author	Pavlopoulos, S	en
dc.contributor.author	Santos, A	en
dc.date.accessioned	2014-03-01T01:22:23Z
dc.date.available	2014-03-01T01:22:23Z
dc.date.issued	2005	en
dc.identifier.issn	0140-0118	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/16549
dc.subject	Dynamic PET	en
dc.subject	Feature extraction	en
dc.subject	Positron emission tomography	en
dc.subject	Similarity mapping	en
dc.subject	Standardized uptake value	en
dc.subject.classification	Computer Science, Interdisciplinary Applications	en
dc.subject.classification	Engineering, Biomedical	en
dc.subject.classification	Mathematical & Computational Biology	en
dc.subject.classification	Medical Informatics	en
dc.subject.other	Cells	en
dc.subject.other	Computer simulation	en
dc.subject.other	Diagnosis	en
dc.subject.other	Imaging techniques	en
dc.subject.other	Maps	en
dc.subject.other	Positron emission tomography	en
dc.subject.other	Tumors	en
dc.subject.other	Correlation coefficients (COR)	en
dc.subject.other	Lesions	en
dc.subject.other	Normalization correlation coefficients (NCOR)	en
dc.subject.other	Similarity mapping (SM)	en
dc.subject.other	Oncology	en
dc.subject.other	fluorodeoxyglucose f 18	en
dc.subject.other	article	en
dc.subject.other	calculation	en
dc.subject.other	cancer diagnosis	en
dc.subject.other	cancer localization	en
dc.subject.other	cancer recurrence	en
dc.subject.other	clinical article	en
dc.subject.other	colorectal cancer	en
dc.subject.other	controlled study	en
dc.subject.other	correlation coefficient	en
dc.subject.other	diagnostic procedure	en
dc.subject.other	feasibility study	en
dc.subject.other	giant cell tumor	en
dc.subject.other	human	en
dc.subject.other	human tissue	en
dc.subject.other	image analysis	en
dc.subject.other	positron emission tomography	en
dc.subject.other	reference value	en
dc.subject.other	simulation	en
dc.subject.other	standardization	en
dc.subject.other	Colorectal Neoplasms	en
dc.subject.other	Feasibility Studies	en
dc.subject.other	Fluorodeoxyglucose F18	en
dc.subject.other	Humans	en
dc.subject.other	Image Processing, Computer-Assisted	en
dc.subject.other	Neoplasm Recurrence, Local	en
dc.subject.other	Neoplasms	en
dc.subject.other	Phantoms, Imaging	en
dc.subject.other	Positron-Emission Tomography	en
dc.subject.other	Radiopharmaceuticals	en
dc.title	Feasibility study of the use of similarity maps in the evaluation of oncological dynamic positron emission tomography images	en
heal.type	journalArticle	en
heal.identifier.primary	10.1007/BF02345119	en
heal.identifier.secondary	http://dx.doi.org/10.1007/BF02345119	en
heal.language	English	en
heal.publicationDate	2005	en
heal.abstract	A preliminary study is presented on the potential role of similarity mapping (SM) in the evaluation of oncological dynamic 18F-fluorodeoxyglucose positron emission tomography studies, mainly in lesion localisation and detectability. Similarity maps were calculated using previously described (correlation coefficient (COR) and normalised correlation coefficient (NCOR)) and newly introduced similarity measures (sum of squares coefficient (SSQ), squared sum coefficient (SQS), sum of cubes coefficient (SC) and cubed sum coefficient (CS)). The results were evaluated using simulated and clinical data. The study revealed that the best-suited similarity measure for such applications was the CS similarity coefficient, which provided the best parametric images, delineating structures of interest and supporting the visual interpretation of data sets. It was shown that SM and standardised uptake value (SUV) images had comparable diagnostic performance, although SM was able to offer additional time-related information in a single image. For the case of colorectal recurrences (17 cases), the measured contrast values for the CS and SUV images were 2.36 ± 0.47 and 4.12 ± 0.42, respectively, whereas, for three cases of giant cell tumours, these values were 11.6 ± 2.1 and 11.9 ± 1.8, respectively. © IFMBE: 2005.	en
heal.publisher	PETER PEREGRINUS LTD	en
heal.journalName	Medical and Biological Engineering and Computing	en
dc.identifier.doi	10.1007/BF02345119	en
dc.identifier.isi	ISI:000226938000005	en
dc.identifier.volume	43	en
dc.identifier.issue	1	en
dc.identifier.spage	23	en
dc.identifier.epage	32	en