Design considerations and construction of a small animal PET prototype

Tzanakos, G; Nikolaou, M; Drakoulakos, D; Karamitros, D; Kontaxakis, G; Logaras, E; Panayiotakis, G; Pavlopoulos, S; Skiadas, M; Spyrou, G; Thireou, T; Vamvakas, D

dc.contributor.author	Tzanakos, G	en
dc.contributor.author	Nikolaou, M	en
dc.contributor.author	Drakoulakos, D	en
dc.contributor.author	Karamitros, D	en
dc.contributor.author	Kontaxakis, G	en
dc.contributor.author	Logaras, E	en
dc.contributor.author	Panayiotakis, G	en
dc.contributor.author	Pavlopoulos, S	en
dc.contributor.author	Skiadas, M	en
dc.contributor.author	Spyrou, G	en
dc.contributor.author	Thireou, T	en
dc.contributor.author	Vamvakas, D	en
dc.date.accessioned	2014-03-01T01:23:55Z
dc.date.available	2014-03-01T01:23:55Z
dc.date.issued	2006	en
dc.identifier.issn	0168-9002	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/17143
dc.subject	FPGA	en
dc.subject	Monte Carlo simulation	en
dc.subject	Photomultiplier tube	en
dc.subject	Positron emission tomography	en
dc.subject	PSPMT	en
dc.subject	Small animal PET	en
dc.subject.classification	Instruments & Instrumentation	en
dc.subject.classification	Nuclear Science & Technology	en
dc.subject.classification	Physics, Particles & Fields	en
dc.subject.classification	Spectroscopy	en
dc.subject.other	Computer simulation	en
dc.subject.other	Field programmable gate arrays	en
dc.subject.other	Gamma rays	en
dc.subject.other	Monte Carlo methods	en
dc.subject.other	Photomultipliers	en
dc.subject.other	Positron emission tomography	en
dc.subject.other	Block detectors	en
dc.subject.other	Gamma ray detectors	en
dc.subject.other	Position determination	en
dc.subject.other	Position sensitive photomultiplier tube	en
dc.subject.other	Medical imaging	en
dc.title	Design considerations and construction of a small animal PET prototype	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.nima.2006.08.114	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.nima.2006.08.114	en
heal.language	English	en
heal.publicationDate	2006	en
heal.abstract	We are developing a small animal PET scanner consisting of two block detectors, each made of 216 BGO crystals of dimensions 3.75 mm x 3.75 mm x 20 mm, cylindrically arranged and coupled to a position-sensitive photomultiplier tube (82486 PSPMT). Our design was based on a very detailed Monte Carlo, that simulates the function of a PET scanner from the system level down to the individual gamma-ray detectors. We have made laboratory measurements of the individual detector performance as well as measurements of characteristics of the PSPMTs. The two detector blocks which will form the basic tomographic unit have been assembled. We are developing electronics to individually process (amplify and digitize) anode signals, and use field programmable gate arrays (FPGAs) in the position determination and energy measurement of the gamma-rays. At present, as an intermediate step, we are using the electronics supplied from Hamamatsu to study various aspects of the system and produce initial images. (c) 2006 Published by Elsevier B.V.	en
heal.publisher	ELSEVIER SCIENCE BV	en
heal.journalName	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment	en
dc.identifier.doi	10.1016/j.nima.2006.08.114	en
dc.identifier.isi	ISI:000243241300020	en
dc.identifier.volume	569	en
dc.identifier.issue	2 SPEC. ISS.	en
dc.identifier.spage	235	en
dc.identifier.epage	239	en