Proton beam profiling in soft biological matter by detailed Monte Carlo simulation

Emfietzoglou, D; Nikjoo, H; Papamichael, G; Pathak, A

dc.contributor.author	Emfietzoglou, D	en
dc.contributor.author	Nikjoo, H	en
dc.contributor.author	Papamichael, G	en
dc.contributor.author	Pathak, A	en
dc.date.accessioned	2014-03-01T01:24:54Z
dc.date.available	2014-03-01T01:24:54Z
dc.date.issued	2006	en
dc.identifier.issn	0168-583X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/17501
dc.subject	Microdosimetry	en
dc.subject	Monte Carlo	en
dc.subject	Protons	en
dc.subject	Water	en
dc.subject.classification	Instruments & Instrumentation	en
dc.subject.classification	Nuclear Science & Technology	en
dc.subject.classification	Physics, Atomic, Molecular & Chemical	en
dc.subject.classification	Physics, Nuclear	en
dc.subject.other	Carrier concentration	en
dc.subject.other	Computer simulation	en
dc.subject.other	Ions	en
dc.subject.other	Monte Carlo methods	en
dc.subject.other	Protons	en
dc.subject.other	Biological tissue	en
dc.subject.other	Dielectric response	en
dc.subject.other	Electronic energy density	en
dc.subject.other	Microdosimetry	en
dc.subject.other	Proton beams	en
dc.title	Proton beam profiling in soft biological matter by detailed Monte Carlo simulation	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.nimb.2006.03.055	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.nimb.2006.03.055	en
heal.language	English	en
heal.publicationDate	2006	en
heal.abstract	Distributions of relevance to proton beam profiling in soft biological matter are obtained by our Monte Carlo track structure code (MC4), which simulates in an event-by-event mode the electronic losses of light ions and all their secondary electrons in water. We present results on electronic energy density and clustering of interaction events around MeV proton tracks which are associated with important ""local track"" parameters. The detailed character of the simulation based on single-collision cross sections for all the elementary interaction processes allows a probing resolution of the order of nanometers. Since soft biological tissue exists in a liquid/solid like state we compare results obtained by both the oscillator strength properties of the water molecule and the dielectric response of liquid water. Their differences in terms of the nanometric pattern of proton tracks is examined. © 2006 Elsevier B.V. All rights reserved.	en
heal.publisher	ELSEVIER SCIENCE BV	en
heal.journalName	Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms	en
dc.identifier.doi	10.1016/j.nimb.2006.03.055	en
dc.identifier.isi	ISI:000239545000162	en
dc.identifier.volume	249	en
dc.identifier.issue	1-2 SPEC. ISS.	en
dc.identifier.spage	670	en
dc.identifier.epage	672	en