Rearrangement of 5-benzoyl-3(2H)-isothiazol-3-ones to 6-benzoyl 2,3-dihydro-1,3-thiazin-4(2H)-ones

Tsolomiti, G; Tsolomiti, K; Tsolomitis, A

dc.contributor.author	Tsolomiti, G	en
dc.contributor.author	Tsolomiti, K	en
dc.contributor.author	Tsolomitis, A	en
dc.date.accessioned	2014-03-01T01:25:03Z
dc.date.available	2014-03-01T01:25:03Z
dc.date.issued	2006	en
dc.identifier.issn	0793-0283	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/17519
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-33747167136&partnerID=40&md5=29f2c2596d3001951dc1a9b737528f53	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	ISOTHIAZOLE CHEMISTRY	en
dc.subject.other	N-ETHYL-3-ISOTHIAZOLONE	en
dc.title	Rearrangement of 5-benzoyl-3(2H)-isothiazol-3-ones to 6-benzoyl 2,3-dihydro-1,3-thiazin-4(2H)-ones	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2006	en
heal.abstract	5-Benzoyl-3(2H)-isothiazol-3-ones 4 were converted to the corresponding isomeric 6-benzoyl-2-substituted-2,3-dihydro-1,3-thiazin-4(2H)-ones 13 by the following reaction sequence: the preparation of aroylpropionamides (3), the conversion of (3) to aroylisothiazolones (4), the protection, by ketalization, of the aroyl carbonyl group of (4), the transformation of isothiazolone ketals (11) to the corresponding thiazinone ketals (12) and finally the deketalization reaction to aroylthiazinones (13) in good overall yields.	en
heal.publisher	FREUND PUBLISHING HOUSE LTD	en
heal.journalName	Heterocyclic Communications	en
dc.identifier.isi	ISI:000240069500017	en
dc.identifier.volume	12	en
dc.identifier.issue	3-4	en
dc.identifier.spage	247	en
dc.identifier.epage	252	en