A new route to synthesis of 2,5,7-substituted 1,5-benzothiazepin-4(5H)-ones from tertiary 3-benzoylpropionamides

Tsolomiti, G; Tsolomiti, K; Tsolomitis, A

dc.contributor.author	Tsolomiti, G	en
dc.contributor.author	Tsolomiti, K	en
dc.contributor.author	Tsolomitis, A	en
dc.date.accessioned	2014-03-01T01:27:46Z
dc.date.available	2014-03-01T01:27:46Z
dc.date.issued	2008	en
dc.identifier.issn	0793-0283	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/18563
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-43749091719&partnerID=40&md5=ae36880f33bdb4611ad576155d0160f0	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	THIONYL CHLORIDE	en
dc.subject.other	PHARMACOLOGICAL PROPERTIES	en
dc.subject.other	CALCIUM-ANTAGONISTS	en
dc.subject.other	OXIDATIONS	en
dc.subject.other	MECHANISM	en
dc.subject.other	KETONES	en
dc.subject.other	ACIDS	en
dc.title	A new route to synthesis of 2,5,7-substituted 1,5-benzothiazepin-4(5H)-ones from tertiary 3-benzoylpropionamides	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2008	en
heal.abstract	Tertiary amides of 3-benzoylpropionic acid have been found to be converted, on reaction with excess thionyl chloride, via the intermediate 3-sulfenyl chlorides of 3-benzoylacrylamides, followed by an intramolecular Friedel-Crafts reaction, to 2,5,7-substituted 1,5-benzothiazepin-4(5H)-ones.	en
heal.publisher	FREUND PUBLISHING HOUSE LTD	en
heal.journalName	Heterocyclic Communications	en
dc.identifier.isi	ISI:000260108100010	en
dc.identifier.volume	14	en
dc.identifier.issue	1-2	en
dc.identifier.spage	63	en
dc.identifier.epage	68	en