Application of the OECD 301F respirometric test for the biodegradability assessment of various potential endocrine disrupting chemicals

Stasinakis, AS; Petalas, AV; Mamais, D; Thomaidis, NS

dc.contributor.author	Stasinakis, AS	en
dc.contributor.author	Petalas, AV	en
dc.contributor.author	Mamais, D	en
dc.contributor.author	Thomaidis, NS	en
dc.date.accessioned	2014-03-01T01:27:56Z
dc.date.available	2014-03-01T01:27:56Z
dc.date.issued	2008	en
dc.identifier.issn	0960-8524	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/18646
dc.subject	Activated sludge	en
dc.subject	Biodegradation kinetics	en
dc.subject	EDCs	en
dc.subject	Respirometry	en
dc.subject	Wastewater	en
dc.subject.classification	Agricultural Engineering	en
dc.subject.classification	Biotechnology & Applied Microbiology	en
dc.subject.classification	Energy & Fuels	en
dc.subject.other	Activated sludge process	en
dc.subject.other	Biodegradation	en
dc.subject.other	Hormones	en
dc.subject.other	Phenols	en
dc.subject.other	Toxicity	en
dc.subject.other	Biodegradation kinetics	en
dc.subject.other	Respirometry	en
dc.subject.other	Wastewater treatment	en
dc.subject.other	4 n nonylphenol	en
dc.subject.other	4,4' isopropylidenediphenol	en
dc.subject.other	endocrine disruptor	en
dc.subject.other	nonanoic acid	en
dc.subject.other	nonylphenol diethoxylate	en
dc.subject.other	nonylphenol monoethoxylate	en
dc.subject.other	perfluorononanoate	en
dc.subject.other	perfluorooctanoic acid	en
dc.subject.other	phenol derivative	en
dc.subject.other	phthalic acid bis(2 ethylhexyl) ester	en
dc.subject.other	triclosan	en
dc.subject.other	fluorocarbon	en
dc.subject.other	nonylphenol	en
dc.subject.other	octanoic acid derivative	en
dc.subject.other	Activated sludge process	en
dc.subject.other	Biodegradation	en
dc.subject.other	Hormones	en
dc.subject.other	Phenols	en
dc.subject.other	Toxicity	en
dc.subject.other	Wastewater treatment	en
dc.subject.other	activated sludge	en
dc.subject.other	bacterium	en
dc.subject.other	biodegradation	en
dc.subject.other	endocrine disruptor	en
dc.subject.other	half life	en
dc.subject.other	organic compound	en
dc.subject.other	reaction kinetics	en
dc.subject.other	respiration	en
dc.subject.other	toxicity test	en
dc.subject.other	wastewater	en
dc.subject.other	water treatment	en
dc.subject.other	abiotic stress	en
dc.subject.other	activated sludge	en
dc.subject.other	article	en
dc.subject.other	biodegradability	en
dc.subject.other	biotic stress	en
dc.subject.other	biotransformation	en
dc.subject.other	detoxification	en
dc.subject.other	half life time	en
dc.subject.other	kinetics	en
dc.subject.other	manometry	en
dc.subject.other	marine bacterium	en
dc.subject.other	metabolism	en
dc.subject.other	priority journal	en
dc.subject.other	respirometry	en
dc.subject.other	toxicity testing	en
dc.subject.other	Vibrio fischeri	en
dc.subject.other	waste water management	en
dc.subject.other	aerobic metabolism	en
dc.subject.other	bioremediation	en
dc.subject.other	chemistry	en
dc.subject.other	drug effect	en
dc.subject.other	ecosystem restoration	en
dc.subject.other	methodology	en
dc.subject.other	reproducibility	en
dc.subject.other	Bacteria (microorganisms)	en
dc.subject.other	Vibrio fischeri	en
dc.subject.other	Aerobiosis	en
dc.subject.other	Biodegradation, Environmental	en
dc.subject.other	Diethylhexyl Phthalate	en
dc.subject.other	Endocrine Disruptors	en
dc.subject.other	Environmental Remediation	en
dc.subject.other	Fluorocarbons	en
dc.subject.other	Octanoic Acids	en
dc.subject.other	Phenols	en
dc.subject.other	Reproducibility of Results	en
dc.subject.other	Toxicity Tests	en
dc.subject.other	Triclosan	en
dc.subject.other	Vibrio fischeri	en
dc.title	Application of the OECD 301F respirometric test for the biodegradability assessment of various potential endocrine disrupting chemicals	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.biortech.2007.08.002	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.biortech.2007.08.002	en
heal.language	English	en
heal.publicationDate	2008	en
heal.abstract	The biodegradability of several potential endocrine disrupting compounds, namely 4-n-nonylphenol (4-n-NP), nonylphenol monoethoxylate (NP1EO), nonylphenol diethoxylate (NP2EO), bisphenol A (BPA), triclosan (TCS), di-(2-ethylhexyl)-phthalate (DEHP), perfluorooctanoate (PFOA) and perfluorononanoate (PFNA) was evaluated in this study, using OECD method 301F (manometric respirometry test) and activated sludge as inoculum. According to the results, 4-n-NP and BPA meet the strict definition of ready biodegradability and they are not expected to be persistent during the activated sludge process. Partial biodegradation was observed for DEHP (58.7 +/- 5.7%, n = 3). TCS (52.1 +/- 8.5%, n = 3) and NP1EO (25.9 +/- 8.1%, n = 3), indicating their possible biodegradation in wastewater treatment systems, while no biodegradation was observed for NP2EO, PFOA and PFNA. Experiments in the co-presence of a readily biodegradable compound showed the absence of co-metabolic phenomena during 4-n-NP, BPA and TCS biodegradation. Using first order kinetics to describe biodegradation of the target compounds, half-lives of 4.3 +/- 0.6, 1.3 +/- 0.2, 1.8 +/- 0.5, 6.9 +/- 2.6 days were calculated for 4-n-NP, BPA, TCS and DEHP, respectively. Toxicity tests using marine bacterium Vibrio fischeri showed that biodegradation of 4-n-NP, NP1EO, BPA and TCS is a simultaneous detoxification process, while possible abiotic or biotic transformations of NP2EO, DEHP, PFOA and PFNA during respirometric test resulted to significant increase of their toxicities. (c) 2007 Elsevier Ltd. All rights reserved.	en
heal.publisher	ELSEVIER SCI LTD	en
heal.journalName	Bioresource Technology	en
dc.identifier.doi	10.1016/j.biortech.2007.08.002	en
dc.identifier.isi	ISI:000254479300019	en
dc.identifier.volume	99	en
dc.identifier.issue	9	en
dc.identifier.spage	3458	en
dc.identifier.epage	3467	en