Asymmetric synthesis of 2-Substituted 3-amino-4-cyanopyrroles via a two-step procedure consisting of a SNV reaction on ethoxymethylenemalononitrile followed by a Thorpe-Ziegler cyclization

Botsi, S; Tsolomiti, G; Hamilakis, S; Tsolomitis, A

dc.contributor.author	Botsi, S	en
dc.contributor.author	Tsolomiti, G	en
dc.contributor.author	Hamilakis, S	en
dc.contributor.author	Tsolomitis, A	en
dc.date.accessioned	2014-03-01T01:27:57Z
dc.date.available	2014-03-01T01:27:57Z
dc.date.issued	2008	en
dc.identifier.issn	0793-0283	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/18654
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-59049090830&partnerID=40&md5=81b291bbe3cd4c58943aeaee177bcfa6	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	NEUTROPHIL CHEMOTAXIS	en
dc.subject.other	POTENT INHIBITORS	en
dc.subject.other	CARBONYL GROUP	en
dc.subject.other	DERIVATIVES	en
dc.subject.other	ALKYLATION	en
dc.title	Asymmetric synthesis of 2-Substituted 3-amino-4-cyanopyrroles via a two-step procedure consisting of a SNV reaction on ethoxymethylenemalononitrile followed by a Thorpe-Ziegler cyclization	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2008	en
heal.abstract	An asymmetric synthesis of 2-Substituted 3-amino-4-cyanopyrroles via a two-step procedure consisting of a nucleophilic vinylic substitution (S NV), of ethoxymethylenemalononitrile (EMM), with optically pure α-amino acid esters, resulting to the corresponding aminomethylemalononitriles, followed by a Thorpe-Ziegler cyclization, is described.	en
heal.publisher	FREUND PUBLISHING HOUSE LTD	en
heal.journalName	Heterocyclic Communications	en
dc.identifier.isi	ISI:000262829000003	en
dc.identifier.volume	14	en
dc.identifier.issue	4	en
dc.identifier.spage	233	en
dc.identifier.epage	236	en