Development of a rapid and sensitive method for the simultaneous determination of 1,2-dibromoethane, 1,4-dichlorobenzene and naphthalene residues in honey using HS-SPME coupled with GC-MS

Tsimeli, K; Triantis, TM; Dimotikali, D; Hiskia, A

dc.contributor.author	Tsimeli, K	en
dc.contributor.author	Triantis, TM	en
dc.contributor.author	Dimotikali, D	en
dc.contributor.author	Hiskia, A	en
dc.date.accessioned	2014-03-01T01:28:09Z
dc.date.available	2014-03-01T01:28:09Z
dc.date.issued	2008	en
dc.identifier.issn	00032670	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/18732
dc.subject	1,4-Dichlorobenzene	en
dc.subject	Headspace solid-phase microextraction	en
dc.subject	Honey	en
dc.subject	Naphthalene and 1,2-dibromoethane	en
dc.subject	Residues	en
dc.subject.other	Benzene	en
dc.subject.other	Calibration	en
dc.subject.other	Correlation methods	en
dc.subject.other	Gas chromatography	en
dc.subject.other	Mass spectrometry	en
dc.subject.other	Naphthalene	en
dc.subject.other	1,2-dibromoethane	en
dc.subject.other	Headspace solid-phase microextraction	en
dc.subject.other	Honey	en
dc.subject.other	Ion monitoring	en
dc.subject.other	Residues	en
dc.subject.other	Ethane	en
dc.subject.other	1,2 dibromoethane	en
dc.subject.other	1,4 dichlorobenzene	en
dc.subject.other	dimeticone	en
dc.subject.other	naphthalene	en
dc.subject.other	sodium chloride	en
dc.subject.other	accuracy	en
dc.subject.other	adsorption	en
dc.subject.other	article	en
dc.subject.other	calibration	en
dc.subject.other	concentration (parameters)	en
dc.subject.other	correlation coefficient	en
dc.subject.other	gas chromatography	en
dc.subject.other	headspace solid phase microextraction	en
dc.subject.other	honey	en
dc.subject.other	ion monitoring	en
dc.subject.other	mass spectrometry	en
dc.subject.other	measurement	en
dc.subject.other	priority journal	en
dc.subject.other	sensitivity analysis	en
dc.subject.other	solid phase microextraction	en
dc.subject.other	standard	en
dc.subject.other	temperature	en
dc.subject.other	thickness	en
dc.subject.other	time	en
dc.title	Development of a rapid and sensitive method for the simultaneous determination of 1,2-dibromoethane, 1,4-dichlorobenzene and naphthalene residues in honey using HS-SPME coupled with GC-MS	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.aca.2008.03.049	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.aca.2008.03.049	en
heal.publicationDate	2008	en
heal.abstract	A new method for the simultaneous determination of 1,4-dichlorobenzene (p-DCB), naphthalene and 1,2-dibromoethane (1,2-DBE) residues in honey has been developed. Analysis is carried out using gas chromatography-mass spectrometry (GC/MS) in selected ion monitoring mode (SIM), after extraction and preconcentration of target analytes by headspace solid-phase microextraction (HS-SPME), with a 100 μm film thickness polydimethylsiloxane (PDMS) fiber. Several parameters affecting the extension of the adsorption process (i.e., addition of salt, extraction time, extraction temperature) were studied. The optimal conditions for the determination of these analytes were established. The proposed HS-SPME method showed good sensitivity, without carryover between the samples. Linearity was studied from 5 to 2500 μg kg-1 for p-DCB, 0.5 to 500 μg kg-1 for naphthalene and 5 to 500 μg kg-1 honey for 1,2-DBE with correlation coefficients (r2) ranging from 0.9901 to 0.9999. Precision was assessed and both intra and inter-day R.S.D.s (%) were below 6.3%. The detection limits were found to be 1, 0.1 and 2 μg kg-1 honey for p-DCB, naphthalene and 1,2-DBE, respectively. The percentage recoveries that were evaluated with the proposed HS-SPME method and the standard addition calibration technique gave values among 72.8 and 104.3% for measurements in samples spiked with one target analyte or mixtures of the three. This method has been applied for the analysis of unknown honey samples. The results showed an excellent applicability of the proposed method for the determination of the target compounds in honey samples. © 2008 Elsevier B.V. All rights reserved.	en
heal.journalName	Analytica Chimica Acta	en
dc.identifier.doi	10.1016/j.aca.2008.03.049	en
dc.identifier.volume	617	en
dc.identifier.issue	1-2	en
dc.identifier.spage	64	en
dc.identifier.epage	71	en