Modified Mukaiyama reaction for the synthesis of quinoline alkaloid analogues: Total synthesis of 3,3-diisopentenyl-N-methylquinoline-2,4-dione

Zikou, LC; Igglessi-Markopoulou, O

dc.contributor.author	Zikou, LC	en
dc.contributor.author	Igglessi-Markopoulou, O	en
dc.date.accessioned	2014-03-01T01:28:47Z
dc.date.available	2014-03-01T01:28:47Z
dc.date.issued	2008	en
dc.identifier.issn	0039-7881	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/18973
dc.subject	Lewis acids	en
dc.subject	fused-ring systems	en
dc.subject	aldol reactions	en
dc.subject	quinolines	en
dc.subject	natural products	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	C-13 NMR-SPECTRA	en
dc.subject.other	ESENBECKIA-ALMAWILLIA	en
dc.subject.other	KETENE	en
dc.subject.other	DERIVATIVES	en
dc.subject.other	RUTACEAE	en
dc.subject.other	3,3-DIISOPENTENYL-N-METHYL-2,4-QUINOLDIONE	en
dc.subject.other	CONSTITUENTS	en
dc.subject.other	ACETALS	en
dc.title	Modified Mukaiyama reaction for the synthesis of quinoline alkaloid analogues: Total synthesis of 3,3-diisopentenyl-N-methylquinoline-2,4-dione	en
heal.type	journalArticle	en
heal.identifier.primary	10.1055/s-2008-1067085	en
heal.identifier.secondary	http://dx.doi.org/10.1055/s-2008-1067085	en
heal.language	English	en
heal.publicationDate	2008	en
heal.abstract	A general synthetic approach, capable of accessing a diverse range of 3,3-disubstituted quinoline-2,4-diones and 1,8-naphthyridine-2,4-diones via titanium tetrachloride catalyzed C-acylation of silyl ketene acetals is described. The suggested methodological platform is surveyed using different reaction conditions and is applied to the total syntheses of 3,3-diisopentenyl-N-methylquinoline-2,4-dione and 3-demethyl-N-methylatanine.	en
heal.publisher	GEORG THIEME VERLAG KG	en
heal.journalName	SYNTHESIS-STUTTGART	en
dc.identifier.doi	10.1055/s-2008-1067085	en
dc.identifier.isi	ISI:000257284900007	en
dc.identifier.issue	12	en
dc.identifier.spage	1861	en
dc.identifier.epage	1866	en