Peptide Finder: Mapping measured molecular masses to peptides and proteins

Alexandridou, A; Tsangaris, GTh; Vougas, K; Nikita, K; Spyrou, G

dc.contributor.author	Alexandridou, A	en
dc.contributor.author	Tsangaris, GTh	en
dc.contributor.author	Vougas, K	en
dc.contributor.author	Nikita, K	en
dc.contributor.author	Spyrou, G	en
dc.date.accessioned	2014-03-01T01:28:59Z
dc.date.available	2014-03-01T01:28:59Z
dc.date.issued	2008	en
dc.identifier.issn	1367-4803	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/19063
dc.subject	Molecular Mass	en
dc.subject.classification	Biochemical Research Methods	en
dc.subject.classification	Biotechnology & Applied Microbiology	en
dc.subject.classification	Computer Science, Interdisciplinary Applications	en
dc.subject.classification	Mathematical & Computational Biology	en
dc.subject.classification	Statistics & Probability	en
dc.subject.other	peptide	en
dc.subject.other	protein	en
dc.subject.other	amino acid sequence	en
dc.subject.other	article	en
dc.subject.other	computer program	en
dc.subject.other	isoelectric point	en
dc.subject.other	matrix assisted laser desorption ionization time of flight mass spectrometry	en
dc.subject.other	molecular weight	en
dc.subject.other	priority journal	en
dc.subject.other	protein analysis	en
dc.subject.other	proteomics	en
dc.subject.other	Databases, Protein	en
dc.subject.other	Molecular Weight	en
dc.subject.other	Peptides	en
dc.subject.other	Proteins	en
dc.subject.other	Proteomics	en
dc.subject.other	Software	en
dc.subject.other	Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	en
dc.title	Peptide Finder: Mapping measured molecular masses to peptides and proteins	en
heal.type	journalArticle	en
heal.identifier.primary	10.1093/bioinformatics/btn413	en
heal.identifier.secondary	http://dx.doi.org/10.1093/bioinformatics/btn413	en
heal.language	English	en
heal.publicationDate	2008	en
heal.abstract	The identification of unknown amino acid sequences of peptides as well as protein identification is of great significance in proteomics. Here, we present a publicly available web application that facilitates a high resolution mapping of measured molecular masses to peptides and proteins, irrespectively of the enzyme/digestion method used. Furthermore, multi-filtering may be applied in terms of measured mass tolerance, molecular mass and isoelectric point range as well as pattern matching to refine the results. This approach serves complementary to the existing solutions for protein identification and gives insights in novel peptides discovery and protein identification at the cases where the identification scores from the other approaches may be below significance threshold. Peptide Finder has been proven useful in proteomics procedures with experimental data from MALDI-TOF. © The Author 2008. Published by Oxford University Press. All rights reserved.	en
heal.publisher	OXFORD UNIV PRESS	en
heal.journalName	Bioinformatics	en
dc.identifier.doi	10.1093/bioinformatics/btn413	en
dc.identifier.isi	ISI:000259581900026	en
dc.identifier.volume	24	en
dc.identifier.issue	19	en
dc.identifier.spage	2267	en
dc.identifier.epage	2269	en