Detection and isolation of antiatherogenic and antioxidant substances present in olive mill wastes by a novel filtration system

Stamatakis, G; Tsantila, N; Samiotaki, M; Panayotou, GN; Dimopoulos, AC; Halvadakis, CP; Demopoulos, CA

dc.contributor.author	Stamatakis, G	en
dc.contributor.author	Tsantila, N	en
dc.contributor.author	Samiotaki, M	en
dc.contributor.author	Panayotou, GN	en
dc.contributor.author	Dimopoulos, AC	en
dc.contributor.author	Halvadakis, CP	en
dc.contributor.author	Demopoulos, CA	en
dc.date.accessioned	2014-03-01T01:30:09Z
dc.date.available	2014-03-01T01:30:09Z
dc.date.issued	2009	en
dc.identifier.issn	0021-8561	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/19484
dc.subject	Atherosclerosis	en
dc.subject	Diatomite	en
dc.subject	Filtration	en
dc.subject	Olive mill wastewater	en
dc.subject	Olive oil	en
dc.subject	PAF	en
dc.subject	Zeolite	en
dc.subject.classification	Agriculture, Multidisciplinary	en
dc.subject.classification	Chemistry, Applied	en
dc.subject.classification	Food Science & Technology	en
dc.subject.other	antioxidant	en
dc.subject.other	antithrombocytic agent	en
dc.subject.other	dyes, reagents, indicators, markers and buffers	en
dc.subject.other	infusorial earth	en
dc.subject.other	olive oil	en
dc.subject.other	phenol derivative	en
dc.subject.other	vegetable oil	en
dc.subject.other	zeolite	en
dc.subject.other	article	en
dc.subject.other	atherosclerosis	en
dc.subject.other	chemistry	en
dc.subject.other	filtration	en
dc.subject.other	fruit	en
dc.subject.other	high performance liquid chromatography	en
dc.subject.other	industrial waste	en
dc.subject.other	mass spectrometry	en
dc.subject.other	methodology	en
dc.subject.other	olive tree	en
dc.subject.other	scanning electron microscopy	en
dc.subject.other	Antioxidants	en
dc.subject.other	Atherosclerosis	en
dc.subject.other	Chromatography, High Pressure Liquid	en
dc.subject.other	Diatomaceous Earth	en
dc.subject.other	Filtration	en
dc.subject.other	Fruit	en
dc.subject.other	Indicators and Reagents	en
dc.subject.other	Industrial Waste	en
dc.subject.other	Mass Spectrometry	en
dc.subject.other	Microscopy, Electron, Scanning	en
dc.subject.other	Olea	en
dc.subject.other	Phenols	en
dc.subject.other	Plant Oils	en
dc.subject.other	Platelet Aggregation Inhibitors	en
dc.subject.other	Zeolites	en
dc.title	Detection and isolation of antiatherogenic and antioxidant substances present in olive mill wastes by a novel filtration system	en
heal.type	journalArticle	en
heal.identifier.primary	10.1021/jf9016288	en
heal.identifier.secondary	http://dx.doi.org/10.1021/jf9016288	en
heal.language	English	en
heal.publicationDate	2009	en
heal.abstract	Olive mill waste water (OMVVW) is a major environmental issue in the Mediterranean. We address this problem by investigating the wastes for the presence of biologically active compounds already detected in both olive oil and pomace. Two initial OMWW samples were filtered using two microporous filtering media: (a) clayey diatomite and (b) zeolitic volcanic tuffs, obtaining three filtered samples from each. All initial and filtrated samples were tested for their activity on platelet activating factor (PAF)-induced aggregation. The results showed that the initial samples contain biologically active compounds (PAF inhibitors) and that in their respective last-eluted filtered samples these compounds are purified. These eluted samples, along with their corresponding initial OMWW, were further separated with HPLC and the purified fractions responsible for the aforementioned biological activity, were further studied using chemical determinations and MS analysis. It was confirmed that the PAF inhibitor present in these fractions resembles the one isolated from olive oil. These results offer a new approach on the OMWW handling by offering an alternative use of this waste as starting material for nutritional and/or pharmaceutical purposes in the future. © 2009 American Chemical Society.	en
heal.publisher	AMER CHEMICAL SOC	en
heal.journalName	Journal of Agricultural and Food Chemistry	en
dc.identifier.doi	10.1021/jf9016288	en
dc.identifier.isi	ISI:000271826200011	en
dc.identifier.volume	57	en
dc.identifier.issue	22	en
dc.identifier.spage	10554	en
dc.identifier.epage	10564	en