HECTOR: Enabling microarray experiments over the hellenic grid infrastructure

Kanaris, I; Mylonakis, V; Chatziioannou, A; Maglogiannis, I; Soldatos, J

dc.contributor.author	Kanaris, I	en
dc.contributor.author	Mylonakis, V	en
dc.contributor.author	Chatziioannou, A	en
dc.contributor.author	Maglogiannis, I	en
dc.contributor.author	Soldatos, J	en
dc.date.accessioned	2014-03-01T01:30:50Z
dc.date.available	2014-03-01T01:30:50Z
dc.date.issued	2009	en
dc.identifier.issn	1570-7873	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/19643
dc.subject	EGEE	en
dc.subject	gLite	en
dc.subject	Grid application enablement	en
dc.subject	Hellasgrid	en
dc.subject	Microarray experiments	en
dc.subject	MPI	en
dc.subject.other	EGEE	en
dc.subject.other	gLite	en
dc.subject.other	Grid application enablement	en
dc.subject.other	Hellasgrid	en
dc.subject.other	Microarray experiments	en
dc.subject.other	MPI	en
dc.subject.other	Bioinformatics	en
dc.subject.other	Computer science	en
dc.subject.other	DNA	en
dc.subject.other	Experiments	en
dc.subject.other	Genes	en
dc.subject.other	MATLAB	en
dc.subject.other	Nucleic acids	en
dc.subject.other	Quality of service	en
dc.subject.other	Grid computing	en
dc.title	HECTOR: Enabling microarray experiments over the hellenic grid infrastructure	en
heal.type	journalArticle	en
heal.identifier.primary	10.1007/s10723-009-9123-6	en
heal.identifier.secondary	http://dx.doi.org/10.1007/s10723-009-9123-6	en
heal.language	English	en
heal.publicationDate	2009	en
heal.abstract	Biologists, medical experts, biochemical engineers and researchers working on DNA microarray experiments are increasingly turning on Grid computing with the scope of leveraging the Grid's computing power, immense storage resources, and quality of service to the expedient processing of a wide range of datasets. In this paper we present a combined experience of grid application experts and bioinformatics scientists in deploying a pilot service enabling computationally efficient processing and analysis of data stemming from microarray experiments. This pilot service is accessible over the Hellenic portion of the EGEE grid and has been demonstrated in the scope of several public events. We highlight the process of grid application enablement, grid deployment challenges, as well as lessons learnt from a bi-annual effort to port and deploy a MATLAB DNA microarray application on a production grid. In addition to describing the parallelization of the application, we also emphasize on the development of a distributed federated database for storing and post-processing the results of the microarray experiments. Overall we believe that our experience could be proven valuable not only to microarray data scientists but also to other Grid users that intend to Grid-enable and deploy their applications. © Springer Science+Business Media B.V. 2009.	en
heal.publisher	SPRINGER	en
heal.journalName	Journal of Grid Computing	en
dc.identifier.doi	10.1007/s10723-009-9123-6	en
dc.identifier.isi	ISI:000272244900009	en
dc.identifier.volume	7	en
dc.identifier.issue	3	en
dc.identifier.spage	395	en
dc.identifier.epage	416	en