Solid-phase synthesis of optically active substituted 2-aminofuranones using an activated carbonate linker

Matiadis, D; Prousis, KC; Igglessi-Markopoulou, O

dc.contributor.author	Matiadis, D	en
dc.contributor.author	Prousis, KC	en
dc.contributor.author	Igglessi-Markopoulou, O	en
dc.date.accessioned	2014-03-01T01:31:56Z
dc.date.available	2014-03-01T01:31:56Z
dc.date.issued	2009	en
dc.identifier.issn	1420-3049	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/19984
dc.subject	2-aminofuranones	en
dc.subject	Acylations	en
dc.subject	Heterocycles	en
dc.subject	Lactones	en
dc.subject	Solid-phase synthesis	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	carbonic acid derivative	en
dc.subject.other	furan derivative	en
dc.subject.other	hydroxyacid	en
dc.subject.other	polystyrene derivative	en
dc.subject.other	Wang resin	en
dc.subject.other	acylation	en
dc.subject.other	article	en
dc.subject.other	chemistry	en
dc.subject.other	synthesis	en
dc.subject.other	Acylation	en
dc.subject.other	Carbonates	en
dc.subject.other	Furans	en
dc.subject.other	Hydroxy Acids	en
dc.subject.other	Polystyrenes	en
dc.title	Solid-phase synthesis of optically active substituted 2-aminofuranones using an activated carbonate linker	en
heal.type	journalArticle	en
heal.identifier.primary	10.3390/molecules14103914	en
heal.identifier.secondary	http://dx.doi.org/10.3390/molecules14103914	en
heal.language	English	en
heal.publicationDate	2009	en
heal.abstract	An efficient three-step solid-phase synthesis of diverse 3,5-disubstituted-2-aminofuranones has been developed. alpha-Hydroxy acids loaded on a nitrophenyl carbonate derivative of Wang resin are used as acylating agents for the C-acylation of active methylene compounds and the resulting intermediates provided, through a cyclative cleavage reaction, the desired product.	en
heal.publisher	MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL-MDPI	en
heal.journalName	Molecules	en
dc.identifier.doi	10.3390/molecules14103914	en
dc.identifier.isi	ISI:000271265300007	en
dc.identifier.volume	14	en
dc.identifier.issue	10	en
dc.identifier.spage	3914	en
dc.identifier.epage	3921	en