Spiradenocylindrocarcinoma. Report of a case with a low-grade component of spiradenocarcinoma and an immunohistochemical study

Apostolou, G; Apostolou, N; Chatzipantelis, P; Biteli, M

dc.contributor.author	Apostolou, G	en
dc.contributor.author	Apostolou, N	en
dc.contributor.author	Chatzipantelis, P	en
dc.contributor.author	Biteli, M	en
dc.date.accessioned	2014-03-01T01:31:58Z
dc.date.available	2014-03-01T01:31:58Z
dc.date.issued	2009	en
dc.identifier.issn	0193-1091	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/19994
dc.subject	Adnexal neoplasm	en
dc.subject	Apocrine	en
dc.subject	Estrogen receptor	en
dc.subject	Spiradenocylindrocarcinoma	en
dc.subject	Spiradenocylindroma	en
dc.subject.classification	Dermatology	en
dc.subject.other	carcinoembryonic antigen	en
dc.subject.other	cycline	en
dc.subject.other	cytokeratin 10	en
dc.subject.other	cytokeratin 13	en
dc.subject.other	cytokeratin 14	en
dc.subject.other	cytokeratin 17	en
dc.subject.other	cytokeratin 18	en
dc.subject.other	cytokeratin 19	en
dc.subject.other	cytokeratin 20	en
dc.subject.other	cytokeratin 5	en
dc.subject.other	cytokeratin 7	en
dc.subject.other	cytokeratin 8	en
dc.subject.other	epithelial membrane antigen	en
dc.subject.other	estrogen receptor	en
dc.subject.other	Ki 67 antigen	en
dc.subject.other	progesterone receptor	en
dc.subject.other	protein p53	en
dc.subject.other	adult	en
dc.subject.other	article	en
dc.subject.other	cancer cell	en
dc.subject.other	cancer diagnosis	en
dc.subject.other	cancer grading	en
dc.subject.other	cancer recurrence	en
dc.subject.other	cancer surgery	en
dc.subject.other	case report	en
dc.subject.other	cylindroma	en
dc.subject.other	female	en
dc.subject.other	genetic polymorphism	en
dc.subject.other	hidradenoma	en
dc.subject.other	human	en
dc.subject.other	human tissue	en
dc.subject.other	immunohistochemistry	en
dc.subject.other	mitosis	en
dc.subject.other	mixed tumor	en
dc.subject.other	priority journal	en
dc.subject.other	scar	en
dc.subject.other	skin appendage	en
dc.subject.other	spiradenocylindroma	en
dc.subject.other	subcutaneous tissue	en
dc.subject.other	Adult	en
dc.subject.other	Carcinoma, Skin Appendage	en
dc.subject.other	Female	en
dc.subject.other	Humans	en
dc.subject.other	Immunohistochemistry	en
dc.subject.other	Neoplasm Recurrence, Local	en
dc.subject.other	Skin Neoplasms	en
dc.subject.other	Tumor Markers, Biological	en
dc.title	Spiradenocylindrocarcinoma. Report of a case with a low-grade component of spiradenocarcinoma and an immunohistochemical study	en
heal.type	journalArticle	en
heal.identifier.primary	10.1097/DAD.0b013e3181a4f75c	en
heal.identifier.secondary	http://dx.doi.org/10.1097/DAD.0b013e3181a4f75c	en
heal.language	English	en
heal.publicationDate	2009	en
heal.abstract	Spiradenocylindrocarcinoma is a very rare malignant cutaneous neoplasm of the folliculosebaceous-apocrine unit. We report a case of this hybrid tumor in a 42-year-old woman. The tumor consisted of 2 circumscribed nodules with areas of cylindrocarcinoma and low-grade spiradenocarcinoma. In the overlapping areas, both spiradenomatous and cylindromatous features were observed. Expansion of the tumor beyond the fibrous pseudocapsule into the adjacent tissue was present. Furthermore, tumor cells were demonstrating mild to moderate pleomorphism and an increased mitotic index. p53 and ki-67 were among the positive immunohistochemical markers. A relatively small number of tumor cells expressed estrogen receptors. The aim of this study was to investigate the nature of this rare tumor of the skin appendages. © 2009 Lippincott Williams & Wilkins, Inc.	en
heal.publisher	LIPPINCOTT WILLIAMS & WILKINS	en
heal.journalName	American Journal of Dermatopathology	en
dc.identifier.doi	10.1097/DAD.0b013e3181a4f75c	en
dc.identifier.isi	ISI:000268341900013	en
dc.identifier.volume	31	en
dc.identifier.issue	6	en
dc.identifier.spage	594	en
dc.identifier.epage	598	en