Application of ion mobility spectrometry for the detection of human urine

Rudnicka, J; Mochalski, P; Agapiou, A; Statheropoulos, M; Amann, A; Buszewski, B

dc.contributor.author	Rudnicka, J	en
dc.contributor.author	Mochalski, P	en
dc.contributor.author	Agapiou, A	en
dc.contributor.author	Statheropoulos, M	en
dc.contributor.author	Amann, A	en
dc.contributor.author	Buszewski, B	en
dc.date.accessioned	2014-03-01T01:32:46Z
dc.date.available	2014-03-01T01:32:46Z
dc.date.issued	2010	en
dc.identifier.issn	1618-2642	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/20224
dc.subject	Ion mobility spectrometry	en
dc.subject	Location of trapped victims	en
dc.subject	Urban search and rescue operations	en
dc.subject	Urine markers	en
dc.subject	Volatile organic compounds	en
dc.subject.classification	Biochemical Research Methods	en
dc.subject.classification	Chemistry, Analytical	en
dc.subject.other	2-butanone	en
dc.subject.other	Chemical method	en
dc.subject.other	Collapsed buildings	en
dc.subject.other	Heptanone	en
dc.subject.other	Human urine	en
dc.subject.other	Ion mobility spectrometry	en
dc.subject.other	Ionization sources	en
dc.subject.other	Multi-capillary columns	en
dc.subject.other	Potential techniques	en
dc.subject.other	Propanal	en
dc.subject.other	Quartz sand	en
dc.subject.other	Sand layer	en
dc.subject.other	Urban search and rescue operations	en
dc.subject.other	Urine markers	en
dc.subject.other	Volatile organic	en
dc.subject.other	Volatile species	en
dc.subject.other	Acetone	en
dc.subject.other	Chemical detection	en
dc.subject.other	Gas chromatography	en
dc.subject.other	Ions	en
dc.subject.other	Knowledge based systems	en
dc.subject.other	Quartz	en
dc.subject.other	Spectrometry	en
dc.subject.other	Volatile organic compounds	en
dc.subject.other	Body fluids	en
dc.subject.other	volatile organic compound	en
dc.subject.other	article	en
dc.subject.other	chemistry	en
dc.subject.other	human	en
dc.subject.other	methodology	en
dc.subject.other	relief work	en
dc.subject.other	spectrophotometry	en
dc.subject.other	urine	en
dc.subject.other	Humans	en
dc.subject.other	Relief Work	en
dc.subject.other	Spectrophotometry	en
dc.subject.other	Urine	en
dc.subject.other	Volatile Organic Compounds	en
dc.title	Application of ion mobility spectrometry for the detection of human urine	en
heal.type	journalArticle	en
heal.identifier.primary	10.1007/s00216-010-4147-0	en
heal.identifier.secondary	http://dx.doi.org/10.1007/s00216-010-4147-0	en
heal.language	English	en
heal.publicationDate	2010	en
heal.abstract	The aim of the present study was to evaluate the suitability of ion mobility spectrometry (IMS) for the detection of human urine as an indication of human presence during urban search and rescue operations in collapsed buildings. To this end, IMS with a radioactive ionization source and a multicapillary column was used to detect volatile organic compounds (VOCs) emitted from human urine. A study involving a group of 30 healthy volunteers resulted in the selection of seven volatile species, namely acetone, propanal, 3-methyl-2-butanone, 2-methylpropanal, 4-heptanone, 2-heptanone and octanal, which were detected in all samples. Additionally, a preliminary study on the permeation of urine volatiles through the materials surrounding the voids of collapsed buildings was performed. In this study, quartz sand was used as a representative imitating material. Four compounds, namely 3-methyl-2-butanone, octanal, acetone and 2-heptanone, were found to permeate through the sand layers during all experiments. Moreover, their permeation times were the shortest. Although IMS can be considered as a potential technique suitable for the detection, localization and monitoring of VOCs evolved from human urine, further investigation is necessary prior to selecting field chemical methods for the early location of trapped victims. © 2010 The Author(s).	en
heal.publisher	SPRINGER HEIDELBERG	en
heal.journalName	Analytical and Bioanalytical Chemistry	en
dc.identifier.doi	10.1007/s00216-010-4147-0	en
dc.identifier.isi	ISI:000283244500024	en
dc.identifier.volume	398	en
dc.identifier.issue	5	en
dc.identifier.spage	2031	en
dc.identifier.epage	2038	en